Anti-protozoal and plasmodial FabI enzyme inhibiting metabolites of <em>Scrophularia lepidota</em> roots (Publications)
glycoside (11). The structures of the new compounds were determined as 3,4-dihydro-methylcatalpol (8) and 6-O-[4''-O-trans-(3,4-dimethoxycinnamoyl)-alpha-L-rhamnopyranosyl]aucubin (scrolepidoside, 9) by
Associations between home- and family-related factors and fruit juice and soft drink intake among 10- to 12-year old children: the ENERGY project (Publications)
modeling, self-efficacy, rewarding, and family consumption). 7915 children (52% girls; mean age=11.7±0.8 years) and 6512 parents (83% women; mean age=41.4±5.3 years) completed the questionnaire. Multilevel
Risk of<em> vibrio</em> transmission linked to the consumption of crustaceans in coastal towns of Côte d'Ivoire (Publications)
conducted among 120 randomly selected households in Abidjan. Overall, Vibrio spp. were isolated from 7.8% of the crustacean samples studied, at levels as high as 6.3 log CFU/g. Of the Vibrio strains identified
Cynaropicrin: the first plant natural product with <em>in vivo</em> activity against <em>Trypanosoma brucei</em> (Publications)
adenocarcinoma cells, and murine peritoneal macrophages were measured, and selectivity indices of 7.8, 62, and 9.5 were determined. This is the first report of a plant natural product with potent IN VIVO
Antiprotozoal isoflavan quinones from <em>Abrus precatorius</em> ssp. <em>africanus</em> (Publications)
(1) and abruquinone G (2), and three isoflavan quinones, abruquinone I (3), abruquinone B (4), and 7,8,3''5'-tetramethoxyisoflavan-1',4'-quinone (5). Compounds 1 and 3 were new natural products. The absolute
Pulsed radio-frequency electromagnetic fields: dose-dependent effects on sleep, the sleep EEG and cognitive performance (Publications)
2-, 3-back task]. Immediately after exposure, night-time sleep was polysomnographically recorded for 8 h. Sleep architecture was not affected by EMF exposure. Analysis of the sleep electroencephalogram (EEG)
Child mortality patterns in rural Tanzania: an observational study on the impact of malaria control interventions (Publications)
interventions on mortality. RESULTS: Child mortality rates decreased by 42.5% from 14.6 c/1000py in 1997 to 8.4 c/1000py in 2009. Analyses revealed the complexity of child mortality patterns and a strong association
Use of B-type natriuretic peptide for the management of women with dyspnea (Publications)
confidence interval 3,854 to 5,708) versus $6,843 in the control group (95% confidence interval 5,611 to 8,074, p = 0.009). In-hospital mortality rates were 4% in the BNP group and 10% in the control group (p
Use of poly(amidoamine) drug conjugates for the delivery of antimalarials to <em>Plasmodium</em> (Publications)
conjugate containing from 14.2 to 32.9% (w/w) active principle. Intraperitoneal administration of 0.8mg/kg chloroquine as either AGMA1 or ISA23 salts cured P. yoelii-infected mice, whereas control animals
Synthesis and antiparasitic activity of new bis-arylimidamides: DB766 analogs modfied in the terminal groups (Publications)
showed good activity versus T. cruzi, T. brucei rhodesiense and P. falciparum (IC50 = 200 nM, 32 nM and 8.5 nM, respectively). Three compounds (7g, 7i, 7j) with thiazole replacing the pyridine rings gave low
