Discovery of antischistosomal drug leads based on tetraazamacrocyclic derivatives and their metal complexes (Publications)
0.10 muM for PZQ) against adult worms. In vivo, the worm burden reductions were 12.3%, 88.4% and 74.8%, respectively at a 400 mg/kg single oral dose. The Fe2+-complex exhibited activity in vivo comparable
Extremely low-frequency magnetic fields and risk of childhood leukemia: a risk assessment by the ARIMMORA consortium (Publications)
conclusions. Although experiments in different animal strains showed exposure-related decreases of CD8+ T-cells, a role in carcinogenesis must be further established. No direct damage of DNA by exposure
Water quality, sanitation, and hygiene conditions in schools and households in Dolakha and Ramechhap districts, Nepal: results from a cross-sectional... (Publications)
household levels were contaminated with thermo-tolerant coliforms. The values of water samples for pH (6.8-7.6), free and total residual chlorine (0.1-0.5 mg/L), mean lead concentration (0.01 mg/L), and mean
The prevalence and diversity of intestinal parasitic infections in humans and domestic animals in a rural Cambodian village (Publications)
hookworms (63.3%), Entamoeba spp. (27.1%) and Strongyloides stercoralis (24.3%). In dogs, hookworm (80.8%), Spirometra spp. (21.3%) and Strongyloides spp. (14.9%) were most commonly detected and in pigs Isospora
Implementation of tuberculosis intensive case finding, isoniazid preventive therapy, and infection control ("Three I's") and HIV-tuberculosis service... (Publications)
countries: 6 (13%) Asia Pacific, 7 (15%), Caribbean, Central and South America, 5 (10%) Central Africa, 8 (17%) East Africa, 14 (30%) Southern Africa, and 7 (15%) West Africa. RESULTS: ICF using symptom-based
The burden of leprosy in Cameroon: fifteen years into the post-elimination era (Publications)
health districts were still to do so by 2014. The number of high-leprosy-burden regions decreased from 8 in 2000 to 1 in 2014. Seven and two regions were respectively medium and low-burdened at the end of
Anti-trypanosomatid elemanolide sesquiterpene lactones from<em> Vernonia lasiopus </em>O. Hoffm (Publications)
ne extract led to the isolation and identification of six elemanolide type sesquiterpene lactones: 8-desacylvernolide, vernolepin, vernomenin, vernodalol, vernodalin and 11,13-dihydrovernodalin. All these
Joint effect of obesity and TNFA variability on asthma: two international cohort studies (Publications)
among nonatopics (OR for G/A and A/A genotypes 6.1, 95% CI 2.5-14.4; OR for G/G genotype 1.7, 95% CI 0.8-3.3). The present findings provide, for the first time, evidence for a complex pattern of interaction
Asthma and the menopause: a systematic review and meta-analysis (Publications)
stratified by intake of menopausal hormone therapy (MHT).RESULTS: Of 76 potentially relevant articles, 8 studies met the inclusion criteria and were included in the review, and 6 in the meta-analysis. There
Associations between selective attention and soil-transmitted helminth infections, socioeconomic status, and physical fitness in disadvantaged... (Publications)
academic achievement in school-aged children. METHODOLOGY: The study cohort included 835 children, aged 8-12 years, from eight primary schools in socioeconomically disadvantaged neighborhoods of Port Elizabeth