Identification of a new locus at 16q12 associated with time-to-asthma onset (Publications)
RESULTS: We detected 5 regions associated with TAO at the genome-wide significant level (P < 5 x 10-8). We evidenced a new locus in the 16q12 region (near cylindromatosis turban tumor syndrome gene [CYLD])
Longitudinal validity of spirometers: a challenge in longitudinal studies (Publications)
(2003) of the same devices revealed a maximal variation of up to 2.6% for FVC, 2.4% for FEV1 and 2.8% for FEF50 across devices with no indication of systematic differences between spirometers. Results
Gender differences in prevalence, diagnosis and incidence of allergic and non-allergic asthma: a population-based cohort (Publications)
investigated in 9091 men and women randomly selected from the general population and followed up after 8-10 years as part of the European Community Respiratory Health Survey. The protocol included assessment
Development of land use regression models for PM2.5, PM2.5 absorbance, PM10 and PMcoarse in 20 European study areas; results of the ESCAPE project (Publications)
of predictor variables, especially traffic intensity. Cross validation R2 results were on average 8-11% lower than model R2. Careful selection of monitoring sites, examination of influential observations
Efficacy of moxidectin versus ivermectin against <em>Strongyloides stercoralis</em> infections: a randomized controlled non-inferiority trial (Publications)
conducted an exploratory, randomized, single-blind trial to evaluate the efficacy and safety of moxidectin (8 mg) versus ivermectin (200 mug/kg) against S. stercoralis infections. Cure rate (CR) against S.stercoralis
Acute gastroenteritis in primary care: a longitudinal study in the Swiss Sentinel Surveillance Network, Sentinella (Publications)
patients received dietary recommendations and/or medical prescriptions; antibiotics were prescribed in 8.5%. Stool testing was initiated in 12.3% of cases; more frequently in patients reporting recent travel
Use of antibody tools to provide serologic evidence of elimination of <em>Lymphatic filariasis</em> in the Gambia (Publications)
Wb123 ranged in age from 3 to 100 years. Overall, Bm14 prevalence was also low (1.5%, 95% CI 0.7-2.8%). Bm14 positivity was significantly associated with older age (P < 0.001). The low levels of antibody
Development of a focused library of triazole-linked privileged-structure-based conjugates leading to the discovery of novel phenotypic hits against... (Publications)
y)propyl)-1H-1,2,3-triazol-4-yl)propyl)-10H-ph enothiazine (12) showed respective IC50 values of 1.8 and 1.9 mug mL(-1) against T. cruzi, together with optimal selectivity. In particular, compound 7 showed
The role of community health workers and local leaders in reducing attrition among participant in the AIDS indicator survey and HIV incidence in a... (Publications)
were revisited and consented to participate at 12 months of follow up. The overall attrition rate was 8.0%. A majority of those lost (54.3%) were less than 25 years of age, male (55.1%), not living in union
Occupational exposures and 20-year incidence of COPD: the European Community Respiratory Health Survey (Publications)
those exposed to gases and fumes (RR 1.5, 95% CI 1.0 to 2.2) and pesticides (RR 2.2, 95% CI 1.1 to 3.8). The combined population attributable fraction for these exposures was 21.0%. INTERPRETATION: These
