Extreme temperatures and stroke mortality: evidence from a multi-country analysis (Publications)
stroke deaths, extreme cold and hot days contributed 11.2 (95% empirical CI, 10.9-11.4) and 0.7 (95% empirical CI, 0.5-0.8) excess deaths, respectively. We found that countries with low gross domestic product [...] heat-related hemorrhagic stroke mortality than countries with high gross domestic product per capita (P=0.02). CONCLUSIONS: Both extreme cold and hot temperatures are associated with an increased risk of dying
A prospective evaluation of the diagnostic accuracy of the point-of-care VISITECT CD4 Advanced Disease test in seven countries (Publications)
s with a CD4 between 0-100, 101-200, 201-300, 301-500, and > 500 cells/µl, VISITECT misclassified 4.5% (95% CI 2.5-7.2%), 12.5 (95% CI 8.0-18.2%), 74.1% (95% CI 67.0-80.5%), 48.0% (95% CI 42.5-53.6%),
<em>Plasmodium falciparum pfhrp2</em> and <em>pfhrp3</em> gene deletions among patients enrolled at 100 health facilities throughout Tanzania:... (Publications)
that parasites with these gene deletions are rare in Tanzania, and estimated that 0.24% (95% confidence interval: 0.08% to 0.39%) of false-negative HRP2-RDTs for symptomatic persons were due to pfhrp2 deletions [...] July 2021. Of 7863 persons of all ages enrolled and providing RDT result and blood sample, 3777 (48.0%) were positive by the national RDT testing for Plasmodium lactate dehydrogenase (pLDH) and/or HRP2
Comparison of NO2 and BC predictions estimated using Google Street View-based and conventional European-wide LUR models in Copenhagen, Denmark (Publications)
NO2 from Google-MM-LUR and 2010 NO2 from EUW-LUR was 0.66, while at residences, this was 0.60. For BC, these were 0.51 across street segments and 0.40 at the residential level. The ratio of percentile
Pre-existing partner-drug resistance to artemisinin combination therapies facilitates the emergence and spread of artemisinin resistance: a consensus... (Publications)
establishment were observed after an increase in frequency of the partner-drug resistance genotype from 0.0 to 0.10. INTERPRETATION: Partner-drug resistance in ACTs facilitates the early emergence of artemisinin [...] artesunate-amodiaquine (ASAQ), or artemether-lumefantrine (AL). The primary outcome was time until 0.25 580Y allele frequency for artemisinin resistance (the establishment time). FINDINGS: Higher frequencies
Effectiveness of an electronic clinical decision support system in improving the management of childhood illness in primary care in rural Nigeria: an... (Publications)
lower oral antimicrobial prescription rates (adjusted OR=2.42 (1.00 to 5.85) and adjusted OR=0.40 (0.22 to 0.73), respectively) in ALMANACH facilities as well as markedly higher rates for referral, com [...] antimalarial prescription, referral, and communication of diagnosis and follow-up advice, assessed at day 0 exit interview. RESULTS: We recruited 1929 children, of which 1021 (53%) attended ALMANACH facilities
Bayesian geostatistical modelling of high-resolution <em>NO</em>2 exposure in Europe combining data from monitors, satellites and chemical transport... (Publications)
CTM (GEOS-Chem) at 0.5 degrees x 0.625 degrees spatial resolution and surface-to-column NO2 ratios. Simulations from the Ensemble of regional CTMs at spatial resolution of 0.1 degrees x 0.1 degrees were extracted
Investigating the effect of recall period on estimates of inpatient out-of-pocket expenditure from household surveys in Vietnam (Publications)
for the 6-month recall period had a significantly lower risk of failing to report the event (RR 0.8 (0.7, 1.0)). The results suggest the best recall period may depend on whether the purpose of a survey is [...] periods. The geometric mean ratio for the 6-month period was estimated to be a multiple of 1.4 (95% CI 0.9, 2.1) times that of the 12-month period. Similarly, there was no evidence of an effect of recall period
Distinct effects of saturated and monounsaturated fatty acids on beta-cell turnover and function (Publications)
DNA fragmentation. In contrast, monounsaturated palmitoleic acid alone (0.5 mmol/l) or in combination with palmitic acid (0.25 or 0.5 mmol/l each) did not affect DNA fragmentation. Increasing concentrations [...] matrix derived from bovine corneal endothelial cells. Exposure of islets to saturated fatty acid (0.5 mmol/l palmitic acid) in medium containing 5.5, 11.1, or 33.3 mmol/l glucose for 4 days resulted in
Malaria: a major health problem within an oil palm plantation around Popondetta, Papua New Guinea (Publications)
Children between five and nine years of age were most affected (40.3%, 95% CI 0.32-0.49). Haemoglobin levels were found to be low; 11.0 g/dl (95% CI 10.8-11.1) for men and 10.4 g/dl (95% CI 10.3-10.5) for women [...] 2006. RESULTS: Malaria prevalence was found to be high: all-age prevalence was 33.5% (95% CI 30.1-37.0) in 723 individuals. Plasmodium falciparum was the dominant species, followed by Plasmodium vivax and
