Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis (Publications)
locus and with two recently identified association signals at 11q13.5 (rs7927894; P = 0.008) and 20q13.33 (rs6010620; P = 0.002). Our results underline the importance of both epidermal barrier function and [...] discovery and replication cohorts combined, including rs479844 upstream of OVOL1 (odds ratio (OR) = 0.88, P = 1.1 x 10(-13)) and rs2164983 near ACTL9 (OR = 1.16, P = 7.1 x 10(-9)), both of which are near
A standardised method for interpreting the association between mutations and phenotypic drug resistance in <em>Mycobacterium tuberculosis</em> (Publications)
capreomycin to 88.2% (85.1-90.9%) for moxifloxacin, with specificity ranging from 90.0% (87.1-92.5%) for moxifloxacin to 99.5% (99.0-99.8%) for amikacin.This study provides a standardised and comprehensive approach [...] sensitivity (95% CI) for rifampicin was 90.3% (89.6-90.9%), while for isoniazid it was 78.2% (77.4-79.0%) and their specificities were 96.3% (95.7-96.8%) and 94.4% (93.1-95.5%), respectively. For second-line
Dealing with crosstalk in electromagnetic field measurements of portable devices (Publications)
and 0.92%). The contribution of DECT to total RF-EMF exposure is typically already low (3.2%), but is further reduced after correction (3.0%). Crosstalk corrections reduced the total exposure by 1.0% on
Retrospective study on the usefulness of pulse oximetry for the identification of young children with severe illnesses and severe pneumonia in a rural... (Publications)
were severe pneumonia. The ROC curves of pulse oximetry (continuous variable) showed an AUC of 0.63, 0.68 and 0.65 for prediction of severe illness, severe pneumonia and hospitalization, respectively. Pulse
Regional differences and trends in breast cancer surgical procedures and their relation to socioeconomic disparities and screening patterns (Publications)
gynaecologists: 1.06). Regions in the French-speaking part (RR: 0.72) and/or with mammographyscreening programmes showed significantly lower rates (RR: 0.87). No difference was found for patients in different [...] in rates were present. Rates were significantly influenced by age [relative rate ratio (RR) 50–69: 0.92, RR 70+:1.25], differences in co-morbidity (RR one co-morbidity: 1.17, RR more than one: 1.35), higher
Associations of various nighttime noise exposure indicators with objective sleep efficiency and self-reported sleep quality: a field study (Publications)
last hour prior to wake-up was most crucial, with an increase in the sleepiness score of 0.31 units (95% CI: 0.08 to 0.54) per 10 dB(A) Leq,1h. Associations for estimated indoor noise were not more pronounced
Interventional cardiac catheterization predictors at Al-Arabi Heart Center in Palestine in 2017 (Publications)
Multivariate logistic regression showed Troponin (RR = 4.5), Age (RR = 1.0), Female gender (RR = 0.4) previous catheterization (RR = 2.0), and existence of diabetes as significant predictors for revascularization
Source of funding and results of studies of health effects of mobile phone use: systematic review of experimental studies (Publications)
were least likely to report a statistically significant result: the odds ratio was 0.11 (95% confidence interval 0.02 to 0.78), compared to studies funded by public agencies or charities. This finding was
<em>In vitro</em> antiplasmodial activity and cytotoxicity of extracts and chromatographic fractions of twigs from <em>Pappea capensi</em>s EckI &... (Publications)
antiplasmodial activity and selectivity. Of all assayed fractions, only N (0.6mug/ml; SI=91), D (0.85mug/ml; SI=37) and E (0.91mug/ml; SI=30) depicted the best antiplasmodial activity and selectivity. [...] were dried and then ground to fine powder. A solvent mixture of dichloromethane: methanol: water (1:0.5:0.5, v/v) was used to extract. The polar extract was separated from the non-polar. The organic extract
Diagnostic performance and comparison of ultrasensitive and conventional rapid diagnostic test, thick blood smear and quantitative PCR for detection... (Publications)
p/microL by TBS. The median prepatent periods in days (ranges) were 14.5 (10-20), 18.0 (15-28), 18.0 (15-20) and 18.0 (16-24) for qPCR, TBS, uRDT and cRDT, respectively; qPCR detected parasitaemia significantly [...] samples not detected by qPCR. TBS and uRDT were more sensitive than cRDT (TBS vs. cRDT p = 0.015; uRDT vs. cRDT p = 0.053), detecting parasitaemias as low as 3.7 parasites/microL (p/microL) (TBS and uRDT)
