biology, with a focus on research and teaching in low- and middle income countries of sub-Saharan Africa. He has been working at various higher education institutions, including the University of Ghana [...] portfolio. The unit has established research grant management, allowing Swiss TPH to exert the consortium lead for collaborative, multicentre (among others) EU projects. Käser teaches on immunology and research
Severe outcomes of malaria in children under time-varying exposure (Publications)
and incidence of malaria pediatric hospitalizations - a proxy of malaria severe outcomes- in East-Africa. We find that life-long exposure dynamics, and subsequent protection patterns in children, substantially [...] population level. Unsteady transmission patterns over a lifetime in children -increasing or decreasing- lead to an exponential relationship of hospitalization rates versus prevalence rather than the asymptotic
Severe outcomes of malaria in children under time-varying exposure (Publications)
and incidence of malaria pediatric hospitalizations - a proxy of malaria severe outcomes- in East-Africa. We find that life-long exposure dynamics, and subsequent protection patterns in children, substantially [...] population level. Unsteady transmission patterns over a lifetime in children -increasing or decreasing- lead to an exponential relationship of hospitalization rates versus prevalence rather than the asymptotic
says Jürg Utzinger, Director of Swiss TPH. "CSRS has further developed into a leading research and development hub in West Africa with high scientific productivity and outstanding capacity building." About
Breast cancer in women by HIV status: a report from the South African National Cancer Registry (Publications)
BACKGROUND: Breast cancer (BC) is the leading cause of cancer-related morbidity and mortality in women living in South Africa, a country with a high HIV burden. However, characteristics of the double burden [...] burden of HIV and BC in South Africa have not been properly investigated. We described characteristics of BC cases by HIV status in South Africa. METHODS: In this nationwide South African study, we obtained
Breast cancer in women by HIV status: a report from the South African National Cancer Registry (Publications)
BACKGROUND: Breast cancer (BC) is the leading cause of cancer-related morbidity and mortality in women living in South Africa, a country with a high HIV burden. However, characteristics of the double burden [...] burden of HIV and BC in South Africa have not been properly investigated. We described characteristics of BC cases by HIV status in South Africa. METHODS: In this nationwide South African study, we obtained
tool as easy to use and leading to better healthcare. “The DYNAMIC project illustrates the virtues of reverse innovation,” said Valérie D'Acremont of Unisanté and Swiss TPH and lead of the DYNAMIC project [...] Wyss, Deputy Director of Swiss TPH. “Thus, the tool has the potential to lead to better health outcomes for children in Africa, and potentially Europe in the future.” ePOCT+ was developed in close col [...] frontline health workers. As a result, more than 6 in 10 children attending...
Databases to Evaluate AIDS (IeDEA) regional research programmes in Southern Africa, Central Africa, East Africa and West Africa as well as the International Agency for Research on Cancer (IARC). The project [...] In sub-Saharan Africa, cervical cancer continues to be the leading cause of cancer-related death among women. This overlaps with a high prevalence of HIV in the region. Women living with HIV are six times [...] tailored to girls and women living with HIV in sub-Saharan Africa to monitor...
Disease in the Meningitis Belt of Sub-Saharan Africa Bacterial meningitis is a medical emergency and remains one of the major health problems in Sub-Saharan Africa. The three most important agents are Neisseria [...] Buruli ulcer, caused by M. ulcerans , is the third most common mycobacterial disease, and Western Africa is the world region most affected by this chronic necrotising disease of the skin and the subcutaneous [...] responses to M. ulcerans . Clinical lesions usually start as painless...
most vulnerable populations in Asia, Sub-Sahara Africa and the Americas. Leading institution in helminth drug development Swiss TPH is one of the leading institutions worldwide in discovering novel treatments
