The genomes of three stocks comprising the most widely utilized live sporozoite <em>Theileria parva</em> vaccine exhibit very different degrees and... (Publications)
Kiambu5 isolate is considerably more divergent, with close to 40,000 SNPs relative to Muguga, including > 8,500 non-synonymous mutations distributed among > 1,700 (42.5 %) of the predicted genes. These genetic
Evaluation of Xpert® MTB/RIF and Ustar EasyNATTM TB IAD for diagnosis of TB lymphadenitis of children in Tanzania (Publications)
diagnosis of TB lymphadenitis in children from a TB-endemic setting in Tanzania. METHODS: Children of 8 weeks to 16 years of age, suspected of having TB lymphadenitis, were recruited at a district hospital
Comparison of the diagnostic accuracy of three rapid tests for the serodiagnosis of hepatic cystic echinococcosis in humans (Publications)
to ELISA. All tests were poorly sensitive in diagnosing inactive cysts (33.3% ELISA and ADAMU-CE, 42.8% DIGFA, 47.6% VIRapid). The reproducibility of all RDTs was good-very good. Band intensity of VIRapid
Detection and characterization of drug-resistant conferring genes in <em>Mycobacterium tuberculosis</em> complex strains: a prospective study in two... (Publications)
6%). The propensity for an isolate to harbour katG S315T mutation was higher in M. tuberculosis (75.8%) than Mycobacterium africanum (51.7%) (p = 0.0000) whereas the opposite was true for inhApro mutations;
Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function (Publications)
HLA-DQB1 and HLA-DQA2 (smallest P(JMA = )4.35×10(-9)), and KCNJ2 and SOX9 (smallest P(JMA = )1.28×10(-8)) were associated with FEV(1)/FVC or FEV(1) in meta-analysis models including SNP main effects, smoking
Single-dose hepatitis A immunization: 7.5-year observational pilot study in Nicaraguan children to assess protective effectiveness and humoral immune... (Publications)
child, representing an estimated protective effectiveness of 98.3% (95% confidence interval, 87.9-99.8). Boosting elicited an average 29.7-fold increase of anti-HAV levels. CONCLUSIONS: In children living
Improving household air, drinking water and hygiene in rural Peru: a community-randomized-controlled trial of an integrated environmental home-based... (Publications)
n and 253 in the attention control group during 12-month follow-up. Mean diarrhoea incidence was 2.8 episodes per child-year in the intervention compared with 3.1 episodes in the control arm. This corresponds
Sensitisation to Ambrosia in Switzerland: a public health threat on the wait (Publications)
test whether an increase in these rates could be observed. METHODS: Among the 6345 participants from 8 areas who provided blood samples in 1991 and 2002, 5823 had valid results for specific IgE against common
Air pollution from road traffic and systemic inflammation in adults: a cross-sectional analysis in the European ESCAPE project (Publications)
participants living on a busy (> 10,000 vehicles/day) road had elevated CRP values (10.2%, 95% CI 2.4-18.8%, compared to persons living in a quiet residential street with less than 1,000 vehicles/day). Annual
Can school-based distribution be used to maintain coverage of long-lasting insecticide treated bed nets: evidence from a large scale programme in... (Publications)
insecticide treated nets. Ownership of at least one LLIN after the first distribution was 76.1% (95% CI 70.8-80.7) in the intervention area and 78.6% (95% CI 74.4-82.3) in the control area. After the second d
