Early target attainment with continuous infusion meropenem and piperacillin/tazobactam and utilization of therapeutic drug monitoring in critically... (Publications)
associated with target attainment. Subsequently, meropenem dosage was decreased or stopped in 35 of 186 (18.8%) and 89 of 186 (47.9%) patients, respectively, and increased in 2 of 186 (1.1%) patients. CONCLUSIONS:
A whole blood intracellular cytokine assay optimised for field site studies demonstrates polyfunctionality of CD4+ T cells in acute scrub typhus (Publications)
in the context of acute scrub typhus infection, by measuring IFN-gamma, TNF and IL-2 in CD4+ and CD8+ T cells in response to the causative agent O. tsutsugamushi (OT). Using an optimised OT antigen preparation
Substance use referral, treatment utilization, and patient costs associated with problematic substance use in people living with HIV in Cape Town,... (Publications)
problematic SU. Qualitative data came from semi-structured interviews with HIV care providers (N = 8), supplemented by patient interviews (N = 15). RESULTS: None of the screened patient participants (N
High levels of surgical antibiotic prophylaxis: implications for hospital-based antibiotic stewardship in Sierra Leone (Publications)
were important factors associated with antibiotic use. Of the 2,482 doses administered, 1,410 (56.8%) were given postoperatively. Preoperative and intraoperative antibiotic use was reported in 645 (26%)
Lessons from a year of COVID-19 in Zambia: reported attendance and mask wearing at large gatherings in rural communities (Publications)
were 30% less likely to report wearing masks (odds ratio [OR] = 0.71, 95% confidence ratio [CI]: 0.6-0.8) than those attending a clinic visit. After controlling for other variables, the odds of self-reported
Magnitude and associated factors of latent tuberculosis infection due to <em>Mycobacterium tuberculosis</em> complex among high-risk groups in urban... (Publications)
the prevalence of LTBI among slaughterhouse workers was significantly higher for both QTF-Plus (96.8%; P /=15 years of exposure (AOR 5.617, 95% CI 1.202-32.198), having an animal at home (AOR 2.735, 95%
Supporting Treatment for Anti-Retroviral Therapy (START) together: protocol for a pilot, randomized, couple-based intervention to promote women's ART... (Publications)
barriers and solutions to medication adherence. Couples are assessed at baseline, post-treatment (8 weeks post-randomization), and follow-up (12 weeks post-randomization). Conclusion: This study will
A review of ambient air pollution exposure assessment methods in determining childhood respiratory health effects in children under five (Publications)
exposure and outcomes at different “windows of susceptibility”: antenatally/specific trimesters (n = 8), infancy (n = 5) and early childhood (n = 6). In most studies, the reported measures of air pollutants
Long-term effect of asthma on the development of obesity among adults: an international cohort study, ECRHS (Publications)
ECRHS I-II (51.5% female, mean (SD) age of 34 (7) years) and 4976 in ECRHS II-III (51.3% female, 42 (8) years). 9% of participants became obese in ECRHS I-II and 15% in ECRHS II-III. The risk of developing
Effectiveness of four different interventions against <em>Schistosoma haematobium</em> in a seasonal transmission setting of Côte d'Ivoire: a cluster... (Publications)
statistically significantly different from the standard strategy (both ORs 0.4, 95% CI = 0.1 to ~1.8). New cases of infection were still observed in all arms at study end. CONCLUSIONS: Biannual MDA was
