The common G-allele of interleukin-18 single-nucleotide polymorphism is a genetic risk factor for atopic asthma. The SAPALDIA Cohort Study (Publications)
increased prevalence of atopic asthma (adjusted odds ratio (OR): 3.63; 95% confidence interval: (1.64-8.02) for GC or GG carriers vs. CC carriers), and no according association with asthma and concomitant
The role of parasitic infections in atopic diseases in rural schoolchildren (Publications)
antibody to A. lumbricoides, was more frequent among farmers' children than non-farmers' children (39.8%vs 31.1%, P = 0.03). This positive serology was found to be significantly associated with high total
Development and validation of a liquid chromatography/mass spectrometry method for pharmacokinetic studies of OZ78, a fasciocidal drug candidate (Publications)
Protein precipitation was used for sample clean up. Separation was performed through a Phenomenex C8(2) analytical column (50.0mmx2.0mm, 5mum) with a mobile phase of acetonitrile (buffer B) and 5mM ammonium
Ozone exposure assessment in a southern California community (Publications)
community. The Harvard ozone passive sampler was used to monitor cohorts of 22 and 18 subjects for 8 weeks during the spring and fall of 1994, respectively. Ozone exposure variables included 12-hr personal
Molecular markers of in vivo <em>Plasmodium vivax</em> resistance to amodiaquine plus sulfadoxine-pyrimethamine: mutations in pvdhfr and pvmdr1 (Publications)
quadruple mutant pvdhfr 57L+58R+61M+117T and pvmdr1 mutation 976F was the best predictor of TF (OR, 8.56; [Formula: see text]). The difference in TF rates between sites was reflected in the genetic dru
Respiratory symptoms following wildfire smoke exposure: airway size as a susceptibility factor (Publications)
stronger in the lowest quartile of the lung function ratio (eg, fire smoke 6+ days: prevalence ratio: 3.8; 95% confidence interval (CI = 2.0-7.2), compared with the remaining quartiles (fire smoke 6+ days:
Spatial dispersion and characterisation of mosquito breeding habitats in urban vegetable-production areas of Abidjan, Côte d'Ivoire (Publications)
breeding sites, respectively, whereas the corresponding percentages in the dry season were 24.3% and 8.6%. The potential breeding sites in an agricultural zone on the periphery of Abidjan were those least
High temperature and hospitalizations for cardiovascular and respiratory causes in 12 European cities (Publications)
admissions increased by +4.5% (95% confidence interval, 1.9-7.3) and +3.1% (95% confidence interval, 0.8-5.5) in the 75+ age group in Mediterranean and North-Continental cities, respectively. In contrast,
NO2 and children's respiratory symptoms in the PATY study (Publications)
ratios for allergic symptoms tended to be higher for the 9-12 year old children compared with the 6-8 year old children. CONCLUSIONS: Evidence for associations between NO2 and respiratory symptoms was robust
Alcohol consumption and other lifestyle factors: avoidable sources of excess lead exposure (Publications)
higher than those of abstinent subjects. Regular smokers had an unconfounded average blood lead level 8% above that of people who never smoked. Place of residence and hourly frequency of cars in that area