Prevalence of drug-resistance mutations and HIV-1 subtypes in a HIV-1 infected COHORT in rural Tanzania (Publications)
gene was determined: K103N (5.0%), Y181C (2.5%), M184V (2.5%), G190A (1.7%) and M41L, K65KR, K70KR and L74LV (0.8%). In samples from 2009 only K103N (3.3%), M184V and T215FY (0.8%) were detected. Initial
Beyond malaria: causes of fever in outpatient Tanzanian children (Publications)
mucosal infection in 1.5%, and meningitis in 0.2%. The cause of fever was undetermined in 3.2% of the children. A total of 70.5% of the children had viral disease, 22.0% had bacterial disease, and 10.9% had parasitic [...] Of 1005 children (22.6% of whom had multiple diagnoses), 62.2% had an acute respiratory infection; 5.0% of these infections were radiologically confirmed pneumonia. A systemic bacterial, viral, or parasitic
Association of long-term exposure to traffic-related air pollution with blood pressure and hypertension in an adult population-based cohort in Spain... (Publications)
were added to the measured SBP levels of medicated participants, the association was beta = 0.78 (95% CI: -0.43, 2.00). NO2 was not associated with hypertension. Associations of NO2 with SBP and DBP were [...] logistic regression. RESULTS: A 10-mug/m3 increase in NO2 levels was associated with 1.34 mmHg (95% CI: 0.14, 2.55) higher SBP in non-medicated individuals, after adjusting for transportation noise. Results
Reductions in malaria and anaemia case and death burden at hospitals following scale-up of malaria control in Zanzibar, 1999-2008 (Publications)
all-cause deaths due to malaria fell from 46% in 1999-2003 to 12% in 2008 (p < 0.01) and that for anaemia from 26% to 4% (p < 0.01). Cases and deaths due to other causes fluctuated or increased over 1999-2008 [...] groups combined, malaria deaths had fallen by an estimated 90% (95% confidence interval 55-98%)(p < 0.025), malaria in-patient cases by 78% (48-90%), and parasitologically-confirmed malaria out-patient
PCR diagnosis of <em>Opisthorchis viverrini</em> and <em>Haplorchis taichui</em> infections in a Lao community in an area of endemicity and comparison... (Publications)
KK smear and FECT were poorer (sensitivities of 91.4% [95% CI, 81.0 to 97.1%,], 62.3% [95% CI, 49.8 to 73.7%], and 49.3% [95% CI, 37.0 to 61.6%], respectively). PCR may be a valuable and sensitive diagnostic [...] confidence interval [CI], 85.8 to 97.9%) and 73.3% (95% CI, 60.3 to 83.9%) and could detect as little as 0.75 pg DNA and 1.32 ng DNA, respectively. The PCR-determined community prevalences of O. viverrini and
Prenatal air pollution exposure and early cardiovascular phenotypes in young adults (Publications)
increase (beta = 1.05, 95% CI 1.01-1.10) in Young's elastic modulus and a 5% decrease (beta = 0.95, 95% CI 0.91-0.99) in distensibility. Mutually adjusted models of pre- and postnatal PM2.5 further suggested
Personal radiofrequency electromagnetic field exposure measurements in Swiss adolescents (Publications)
stations, WLAN access points, and mobile phones in the surroundings) contributed on average 6.0% to the brain dose and 9.0% to the whole-body dose. CONCLUSIONS: RF-EMF exposure of adolescents is dominated by their [...] of adolescents. RESULTS: Main contributors to the total personal RF-EMF measurements of 63.2muW/m2 (0.15V/m) were exposures from mobile phones (67.2%) and from mobile phone base stations (19.8%). WLAN at
Cohort study of somatostatin-based radiopeptide therapy with [(90)Y-DOTA]-TOC versus [(90)Y-DOTA]-TOC plus [(177)Lu-DOTA]-TOC in neuroendocrine... (Publications)
survival than patients receiving [(90)Y-DOTA]-TOC alone (5.51 v 3.96 years; hazard ratio, 0.64; 95% CI, 0.47 to 0.88; P = .006). The rates of severe hematologic toxicities (6.3% v 4.4%; P = .25) and severe
Single ascending dose pharmacokinetic study of tribendimidine in <em>Opisthorchis viverrini</em>-infected patients (Publications)
50 mg tablets, but at higher dosages (200-600 mg) saturation occurred. Median AUC0-24h ratio of dADT to adADT ranged from 0.8 to 26.4 suggesting substantial differences in the acetylation rate. Cure rates [...] 11% (25 mg dose) to 100% (400 mg dose). Cured patients showed significantly higher dADT Cmax and AUC0-24h than uncured patients. CONCLUSIONS: Tribendimidine is a promising drug for the treatment of opi
Community-based surveillance to monitor mortality in a malaria-endemic and Ebola-epidemic setting in rural Guinea (Publications)
13.9-33.1, P < 0.001) in the program area and by 6.6% (95% CI = -17.3-30.5, P = 0.589) in Koundou. Sixty-eight deaths were classified as sEVD and increased by 6.1% (95% CI = 1.3-10.8, P = 0.021). Eighteen
