Global, regional, and national burden of mortality associated with short-term temperature variability from 2000-19: a three-stage modelling study (Publications)
associated with temperature variability, global gridded temperature data with a resolution of 0.5 degrees x 0.5 degrees were used to assess the temperature variability-related mortality burden at the global [...] assess the global temperature variability-related mortality burden at a spatial resolution of 0.5 degrees x 0.5 degrees from 2000-19. Temperature variability was calculated as the SD of the average of the
If I tweet will you cite later? Follow-up on the effect of social media exposure on article downloads and citations (Publications)
There was no difference between intervention and control group in terms of downloads (p = 0.72) and citations (p= 0.30) for all papers and when we stratified by open access status. CONCLUSIONS: Longer observation
Antituberculotic and antiprotozoal activities of primin, a natural benzoquinone: in vitro and in vivo studies (Publications)
Primin showed very potent activity against Trypanosoma brucei rhodesiense (IC50 0.144 microM) and Leishmania donovani (IC50 0.711 microM), and revealed low cytotoxicity (IC50 15.4 microM) on mammalian cells
High genetic diversity of <em>Plasmodium vivax</em> on the north coast of Papua New Guinea (Publications)
of the Madang catchments (27-35%), genetic diversity was similarly high in all populations (He = 0.77-0.98). High genetic diversity, despite a marked difference in infection prevalence, suggests a large
International scale implementation of the CNOSSOS-EU road traffic noise predictin model for epidemiological studies (Publications)
resolution noise model should provide adequate performance for exposure ranking (Spearman's rank = 0.75; p < 0.001), but with relatively large errors in predicted noise levels (RMSE = 4.46 dB(A)).
<em>Strongyloides stercoralis</em> is a cause of abdominal pain, diarrhea and urticaria in rural Cambodia (Publications)
sensation of itching, respectively, during the previous six months; epigastric (11, 55.0%) and peri-umbilical (13, 65.0%) pains were most frequent. Five patients (23.8%) reported having experienced urticaria
Community effectiveness of intermittent preventive treatment for infants (IPTi) in rural southern Tanzania (Publications)
comparison areas (P = 0.06). In a "per protocol" analysis of children who had recently received IPTi, parasite prevalence was 22%, 19 percentage points lower than comparison children (P = 0.01). IPTi can be
beta-Branched acyclic nucleoside analogues as inhibitors of <em>Plasmodium falciparum</em> dUTPase (Publications)
gave a K(i) of 0.5muM against PfdUTPase with selectivity greater than 200-fold compared to the corresponding human enzyme and sub-micromolar growth inhibition of P. falciparum (EC(50) 0.6muM). A crystal
Antiprotozoal activity of 1-phenethyl-4-aminopiperidine derivatives (Publications)
concentrations (IC50) ranging from 0.12 to 10 microM, and 33 compounds active against the chloroquine- and pyrimethamine-resistant K1 strain of P. falciparum (IC50 range, 0.17 to 5 microM). In addition, seven
In vivo investigations of selected diamidine compounds against <em>Trypanosoma evansi</em> using a mouse model (Publications)
infection. Six of the compounds were capable of curing T. evansi-infected mice at drug doses as low as 0.5 and 0.25 mg/kg of body weight administered for 4 consecutive days, and they were more effective than the
