Registration and local production of essential medicines in Uganda (Publications)
Universal access to high quality essential medicines is critical to sustainable development (SDG 3.8). However low- and middle-income countries struggle to ensure access to all medicines on their national
Increasing blood flow increases kt/V(urea) and potassium removal but fails to improve phosphate removal (Publications)
Qb similar to the increase in potassium removal from 53.0 +/- 2.4 to 63.4 +/- 2.6 and to 74.2 +/- 3.8 mMol (p = 0.01). Phosphate removal only improved from 28.1 +/- 1.3 to 31.4 +/- 1.5 (p = 0.050) when
The synthetic peroxide OZ78 is effective against <em>Echinostoma caproni</em> and <em>Fasciola hepatica</em> (Publications)
400-1000 mg/kg OZ78. Fasciola hepatica-infected rats were treated orally with 50-400 mg/kg OZ78 3 and 8-9 weeks post-infection. Worm burden reductions were assessed against untreated control animals. Adult
Nifurtimox-eflornithine combination therapy for second-stage <em>Trypanosoma brucei gambiense</em> sleeping sickness: a randomized clinical trial in... (Publications)
day given intravenously every 12 h for 7 days) plus nifurtimox (15 mg/kg per day given orally every 8 h for 10 days). Patients were observed for 18 months. The study's outcomes were cure and adverse events
Low efficacy of amodiaquine or chloroquine plus sulfadoxine-pyrimethamine against <em>Plasmodium falciparum</em> and <em>P. vivax malaria</em> in... (Publications)
polymerase chain reaction (PCR)-corrected treatment failure rates up to day 28 ranged between 10.3% and 28.8% for AQ plus SP and between 5.6% and 28.6% for CQ plus SP, depending on the region and the year of
Role of immune cells in animal models for inherited neuropathies: facts and visions (Publications)
(CMT) neuropathies. In addition to the characteristic hallmarks of demyelination, elevated numbers of CD8-positive T-lymphocytes and F4/80-positive macrophages are striking features in the nerves of these mice
Reduced lung cancer mortality and exposure to synthetic fluids and biocide in the auto manufacturing industry (Publications)
exposure [MRR 0.63, 95% confidence interval (95% CI) 0.39-0.98] at the 99 (th)percentile of exposure (15.8 mg/m (3)per year). Evidence for an inverse effect was limited to the earlier follow-up period. Effect
Association between physical activity and risk of stroke subtypes: the atherosclerosis risk in communities study (Publications)
intervals (CI) were calculated using Cox regression models. RESULTS: During a median follow-up of 18.8 years, a total of 648 incident ischemic strokes occurred. Significant inverse associations were found
Early assessment of the implementation of a national programme for the prevention of mother-to-child transmission of HIV in Cameroon and the effects... (Publications)
provide PMTCT. Thirty six peripheral facilities (58%) possessed full equipment for HIV-testing and 8 (13%) stocked all PMTCT drugs. Of 137 nurses, 102 (74%) agreed to the two knowledge tests. Fewer than
Analysis of personal and bedroom exposure to ELF-MFs in children in Italy and Switzerland (Publications)
increased geometric mean personal exposure by a factor of 3.3, and bedroom measurements by a factor 6.8 compared to a control group. Repeated measurements within the same subject showed high reproducibility