Causes of hospital admission among people living with HIV worldwide: a systematic review and meta-analysis (Publications)
119 patients, 46%, 95% CI 40-53) and bacterial infections (14?034 patients, 31%, 20-42) were the leading causes of hospital admission. These two categories were the most common causes of hospital admission [...] admission included malnutrition and wasting, parasitic infections, and haematological disorders in the Africa region; respiratory disease, psychiatric disorders, renal disorders, cardiovascular disorders, and [...] (783 patients, 27%, 95% CI 19-34) and bacterial infections (1190...
Impact of scaling up prenatal nutrition interventions on human capital outcomes in low- and middle-income countries: a modeling analysis (Publications)
BACKGROUND: Prenatal nutrition interventions can lead to improved birth outcomes, which in turn are associated with better education and human capital outcomes later in life. OBJECTIVE: We estimated the [...] and $1.34 billion (95% UI: -1.10, 3.10 billion) for BEP supplementation. South Asia and Sub-Saharan Africa tended to have the largest estimated regional gains in school years for scaling up each intervention [...] to other regions. CONCLUSION: Increasing coverage of prenatal nutrition...
Causes of hospital admission among people living with HIV worldwide: a systematic review and meta-analysis (Publications)
119 patients, 46%, 95% CI 40-53) and bacterial infections (14?034 patients, 31%, 20-42) were the leading causes of hospital admission. These two categories were the most common causes of hospital admission [...] admission included malnutrition and wasting, parasitic infections, and haematological disorders in the Africa region; respiratory disease, psychiatric disorders, renal disorders, cardiovascular disorders, and [...] (783 patients, 27%, 95% CI 19-34) and bacterial infections (1190...
Monitoring Swiss TPH has been acting as a LFA since 2003 in a total of 23 different countries in Africa, South East Asia, Middle East, Latin America and the REDCA region. The LFA is independently contracted [...] work plans or assisting the Global Fund in grant negotiations and grant closure. SPMU is currently leading the performance monitoring of Global Fund grants. "After all those years acting as LFAs in different [...] Centre for International Health SPMU is part of the Swiss Centre for...
The Parasite Reduction Ratio (PRR) assay version 2: standardized assessment of <em>Plasmodium falciparum </em>viability after antimalarial... (Publications)
With artemisinin-resistant Plasmodium falciparum parasites emerging in Africa, the need for new antimalarial chemotypes is persistently high. The ideal pharmacodynamic parameters of a candidate drug are [...] parameters can be fed directly into pharmacokinetic/pharmacodynamic models, hence aiding and standardizing lead selection, optimization, and dose prediction. © 2023 by the authors.
Reflections on the 2021 World Malaria Report and the future of malaria control (Publications)
children revealed a systematic underestimation of disease burden over the past two decades; and that Africa has an even greater malaria crisis than previously known. While countries were able to prevent the [...] Report and reflections on the future trajectories: it was informed by an in-depth discussion with leading malaria experts from the World Health Organization (WHO), the Bill & Melinda Gates Foundation, and
Differential gene repertoire in <em>Mycobacterium ulcerans</em> identifies candidate genes for patho-adaptation (Publications)
approximately 7% of the entire M. ulcerans genome. PRINCIPAL FINDINGS: Several different mechanisms leading to loss of functional genes were identified, ranging from pseudogenization, caused by frame shift [...] the classical lineage may contribute to particular virulence of this group comprising isolates from Africa and Australia. Identification of this spectrum of anti-virulence gene candidates expands our und
Schistosomiasis in European travelers and migrants: analysis of 14 years TropNet Surveillance Data (Publications)
(22%) cases; 57.5% of patients were symptomatic. Acute symptoms were reported in 27% of patients leading to earlier presentation within 3 months. Praziquantel was used in all patients to treat schistosomiasis [...] Travelers should be made aware of the risk of schistosomiasis infection when traveling to sub-Saharan Africa. Posttravel consultations particularly for returning expatriates are useful given the high potential
The Parasite Reduction Ratio (PRR) assay version 2: standardized assessment of <em>Plasmodium falciparum </em>viability after antimalarial... (Publications)
With artemisinin-resistant Plasmodium falciparum parasites emerging in Africa, the need for new antimalarial chemotypes is persistently high. The ideal pharmacodynamic parameters of a candidate drug are [...] parameters can be fed directly into pharmacokinetic/pharmacodynamic models, hence aiding and standardizing lead selection, optimization, and dose prediction. © 2023 by the authors.
Reflections on the 2021 World Malaria Report and the future of malaria control (Publications)
children revealed a systematic underestimation of disease burden over the past two decades; and that Africa has an even greater malaria crisis than previously known. While countries were able to prevent the [...] Report and reflections on the future trajectories: it was informed by an in-depth discussion with leading malaria experts from the World Health Organization (WHO), the Bill & Melinda Gates Foundation, and
