Boosting effect of IL-7 in interferon gamma release assays to diagnose <em>Mycobacterium tuberculosis</em> infection (Publications)
release of IFN-gamma in individuals with active TB from 4.2IU/ml (IQR 1.4-6.9IU/ml) to 5.1IU/ml (IQR 1.5-8.1IU/ml, p = 0.0057), and we found an indication of a lower release of both IFN-gamma and IP-10 in p
The epidemiology of chronic kidney disease and the association with non-communicable and communicable disorders in a population of sub-Saharan Africa (Publications)
(1%) (95% CI 0-3%) as very high risk according to KDIGO. History of tuberculosis (OR 3.75, 95% CI 1.66-8.18; p = 0.001) and schistosomiasis (OR 2.49, 95% CI 1.13-5.18; p = 0.02) were associated with CKD. A
Effect of a 20-week physical activity intervention on selective attention and academic performance in children living in disadvantaged neighborhoods:... (Publications)
randomized control trial. METHODS: The study cohort included 663 children from eight primary schools, aged 8-13 years. Data assessment took place between February 2015 and May 2016 following the implementation
Importance of routine viral load monitoring: higher levels of resistance at ART failure in Uganda and Lesotho compared with Switzerland (Publications)
therapy with the first GRT upon virological failure (n = 61) was selected. Results: We found that 50.8% of individuals in the SHCS, 72.5% in Uganda and 81.0% in Lesotho harboured HIV with high-level resistance
Data-driven adult asthma phenotypes based on clinical characteristics are associated with asthma outcomes twenty years later (Publications)
asthma phenotype, ORs (95%CI) for asthma exacerbations varied from 0.9 (0.4 to 2.0) to 4.0 (2.0 to 7.8) and the regression estimates (95%CI) for FEV1% predicted varied from 0.6 (-3.5 to 4.6) to -9.9 (-14
Pharmacokinetics of albendazole, albendazole sulfoxide and albendazole sulfone determined from plasma, blood, dried blood spots and Mitra® samples of... (Publications)
four matrices. The metabolites reached Cmax after approximately 4 h with a t1/2 of approximately 7-8 h. A statistically significant difference in albendazole sulfone's t1/2 as determined by DBS and wet
Subspecies typing of <em>Streptococcus agalactiae</em> based on ribosomal subunit protein mass variation by MADLI-TOF MS (Publications)
Validation of our approach by in-house MALDI-TOF MS analysis of 248 GBS isolates and external analysis of 8 GBS isolates showed that across different laboratories and MALDI-TOF MS platforms, the 28 rsp were detected
A matter of timing: biting by malaria-infected <em>Anopheles</em> mosquitoes and the use of interventions during the night in rural south-eastern... (Publications)
potentially be averted by ITNs under current use patterns. Outdoor exposure accounted for an estimated 11% (8%, 15%) of infective bites in children below school age and 17% (13%, 22%) in older individuals. Maintaining
Systems modelling and simulation to guide targeted investments to reduce youth suicide and mental health problems in a low-middle-income country (Publications)
scenario. Mental health issues among 12 - 17-year-olds are projected to increase from 18.9% (2023) to 27.8% (2031), and substance use issues from 2.29 to 2.49% over the same period. School-based suicide prevention
Effects of a blood-free mosquito diet on fitness and gonotrophic cycle parameters of laboratory reared <em>Anopheles gambiae</em> <em>sensu... (Publications)
reared on BLOODless versus vertebrate blood from founder generation (F(0)) to eighth generation (F(8)). A total of 1000 female mosquitoes were randomly selected from F(0), of which 500 mosquitoes were
