The effects of medicines availability and stock-outs on household's utilization of healthcare services in Dodoma region, Tanzania (Publications)
interval (CI) 1.02-12.04; P = 0.047]. Healthcare utilization was positively associated with household membership in the community health insurance funds (OR 1.97, 95% CI 1.23-3.17; P = 0.005) and exposure to [...] healthcare education (OR 2.75, 95% CI 1.84-4.08; P = 0.000). These results highlight the importance of medicine availability in promoting access to health services in low-income settings. Effective planning
Diagnosis and epidemiology of <em>Strongyloides stercoralis</em> in Cambodia (Publications)
meta-analysis revealed the best pooled cure rate for Ivermectin with 0.97 (95% BCI: 0.94 – 1.00) and Thiabendazole with 0.95 (95% BCI: 0.92 – 1.00). We conclude that Ivermectin is the best available treatment [...] and lowest average density per person observed were 151.2 LPG (range: 28.8 – 410.6 LPG) and 0.03 LPG (range 0 – 0.07 LPG), respectively. Local maxima estimation technique did not detect a pattern of excretion [...] diagnosed were hookworms (63.3%), Entamoeba spp. (27.1%), S....
Diagnosis and epidemiology of <em>Strongyloides stercoralis</em> in Cambodia (Publications)
meta-analysis revealed the best pooled cure rate for Ivermectin with 0.97 (95% BCI: 0.94 – 1.00) and Thiabendazole with 0.95 (95% BCI: 0.92 – 1.00). We conclude that Ivermectin is the best available treatment [...] and lowest average density per person observed were 151.2 LPG (range: 28.8 – 410.6 LPG) and 0.03 LPG (range 0 – 0.07 LPG), respectively. Local maxima estimation technique did not detect a pattern of excretion [...] diagnosed were hookworms (63.3%), Entamoeba spp. (27.1%), S....
The transferability of lipid loci across African, Asian and European cohorts (Publications)
iated loci has consistent effects on serum levels in samples from the UK, Uganda and Greece (r = 0.23-0.28, p < 1.9 x 10(-14)). Overall, there is evidence of reproducibility for ~75% of the major lipid
Changes in household wealth in communities living in proximity to a large-scale copper mine in Zambia (Publications)
the mine was significantly lower at baseline than that of the North-Western province (? 0.54 points; pvalue < 0.001) in 2011, but surpassed the regional average in 2019 (+1.07 points; p-value
Justified concern or exaggerated fear: the risk of anaphylaxis in percutaneous treatment of cystic echinococcosis - a systematic literature review (Publications)
reversible anaphylactic reactions were reported. Lethal anaphylaxis occurred in 0.03% of PT procedures, corresponding to 0.04% of treated cysts, while reversible allergic reactions complicated 1.7% of PTs
Synthesis, inhibition potency, binding mode, and antiprotozoal activities of fluorescent inhibitors of trypanothione reductase based on... (Publications)
that of the respective parent inhibitors. They show K(ic) values for the parasite enzyme down to 0.9+/-0.1 microm and exhibit high selectivity for TR over human glutathione reductase (GR). Despite their
Identification and characterization of trypanocides by functional expression of an adenosine transporter from <em>Trypanosoma</em> <em>brucei</em> in... (Publications)
Cordycepin (3'-deoxyadenosine) was a TbAT1 substrate of high activity against T. brucei rhodesiense (IC50 0.2 nM). Inhibitors of mammalian nucleoside transport were not active, while the flavonol silibinin was [...] bloodstream form trypanosomes. IC50 values to T. brucei rhodesiense and to human carcinoma cells were 0.6 and 140 microM, respectively, indicating a good selectivity towards the parasites. Further studies
Determinants of circulating insulin-like growth factor I and insulin-like growth factor binding protein 3 concentrations in a cohort of Singapore men... (Publications)
respectively (gender difference, P < 0.0001), and mean IGFBP-3 concentrations were 3710 ng/ml and 4147 ng/ml for men and women, respectively (gender difference, P < 0.0001). IGF-I and IGFBP-3 decreased with
Incapacidades físicas em pessoas acometidas pela hanseníase no período pós-alta da poliquimioterapia em um município no norte do Brasil (Publications)
was a significant association between disability and multibacillary disease (p < 0.001) and occurrence of reactions (p < 0.001). The data show that after discharge from multidrug therapy, in order to prevent
