Status of soil-transmitted helminth infections in schoolchildren in Laguna Province, the Philippines: determined by parasitological and molecular... (Publications)
least one type of STH infection (33.8% by KK vs. 78.3% by qPCR), Ascaris lumbricoides (20.5% by KK vs. 60.8% by qPCR) and Trichuris trichiura (23.6% by KK vs. 38.8% by qPCR). Considering the combined results [...] infections with Ancylostoma spp. (4.6%), Necator americanus (2.3%), and Strongyloides stercoralis (0.8%) that were missed by KK. CONCLUSION/SIGNIFICANCE: qPCR may provide new and important diagnostic information
Effect of immediate initiation of antiretroviral treatment on the risk of acquired HIV drug resistance (Publications)
interval) of acquired drug resistance was 3.2% (2.8,3.5) for immediate initiation, 3.1% (2.7,3.3) for initiation with CD4 cell count less than 500 cells/mul, and 2.8% (2.5,3.0) for initiation with CD4 cell count [...] to individuals with baseline in 2005-2015, the corresponding estimates were 1.9% (1.8, 2.5), 1.9% (1.7, 2.4), and 1.8% (1.7, 2.2). CONCLUSION: Our findings suggest that the risk of acquired drug resistance
Prevalence and predictors of <em>Aspergillus</em> seropositivity and chronic pulmonary aspergillosis in an urban tertiary hospital in Sierra Leone: a... (Publications)
than half (104, 52.8%) had been diagnosed with TB in the past, while 53 (26.9%) were on TB treatment at the time of recruitment. Fifty-two (26.4%) patients were HIV positive, 41 (20.8%) were seropositive [...] ve for Aspergillus and 23 (11.6%) had CPA, 2 (3.8%) with current TB and 18 (17.3%) with past TB. Common radiologic abnormalities reported were localized fibrotic changes 62 (31.5%), consolidation 54 (27 [...] 5%), fever 117 (59.4%) and dyspnea 90 (45.7%). Current or past TB infection {aOR...
Heat-related cardiorespiratory mortality: effect modification by air pollution across 482 cities from 24 countries (Publications)
Similarly, cardiovascular mortality increased by 1.6 (95%CI 1.5-1.6), 5.1 (95%CI 5.1-5.2), and 8.7 (95%CI 8.7-8.8) at low, medium, and high levels of O3, respectively. Discussion We observed considerable
Number of comorbidities and their impact on perioperative outcome and costs: a single centre cohort study (Publications)
confounders and mediators. RESULTS: Of 320 enrolled patients, 27 were ASA I (8%), 150 ASA II (47%), 116 ASA III (36%) and 27 ASA IV (8%). The median number of comorbidities per patient was 5 (range 0-18), this [...] increasing with higher ASA class: 1 comorbidity (95% CI 0.0-2.0) in ASA I, 4 comorbidities (3.8-4.2) in ASA II, 9 (8.1-9.9) in ASA III and 12 (10-14) in ASA IV patients. Independent of ASA class, each additional
High prevalence of symptomatic acute HIV infection in an outpatient ward in southern Mozambique: identification and follow-up (Publications)
and assessment of HIV-RNA, CD4 cell counts and percentage of activated CD8 T cells. RESULTS: HIV serotesting revealed that 37.8% (95% confidence interval 32.7-43.2) of the adults had previously undiagnosed [...] cells/microl (interquartile range 239-441) and a median percentage of activated CD8 T cells of 68.4% (interquartile range 59.6-87.8). CONCLUSION: Of patients reporting with fever, 3.3% were shown to be potentially
Prevalence of bovine tuberculosis and risk factor assessment in cattle in rural livestock areas of govuro district in the southeast of Mozambique (Publications)
36.8-42.5) using a diagnostic threshold cut-off according to the World Organization for Animal Health. bTB reactors were found in 13 livestock areas, with prevalence rates ranging from 8.1 to 65.8%. Age [...] breed showed a lower prevalence than crossbred animals (Landim x Brahman) (OR = 0.6, 95% CI: 0.4-0.8). CONCLUSIONS/SIGNIFICANCE: The findings reveal an urgent need for intervention with effective, area-based
Effect of exposure to traffic on lung development from 10 to 18 years of age: a cohort study (Publications)
age is unknown. This study investigated the association between residential exposure to traffic and 8-year lung-function growth. METHODS: In this prospective study, 3677 children (mean age 10 years [SD [...] California communities that represent a wide range in regional air quality. Children were followed up for 8 years, with yearly lung-function measurements recorded. For each child, we identified several indicators [...] residential exposure to traffic from large roads. Regression analysis was...
Association of environmental tobacco smoke at work and forced expiratory lung function among never smoking asthmatics and non-asthmatics. The... (Publications)
associated with FVC (0.7%; -0.4 to +1.8), FEV1 (-0.1%; 95% CI: -1.3 to +1.1) or FEF25-75% (-1.9%; -4.2 to +0.5). Effects were observed among asthmatics (n = 325), FEV1 (-4.8%; 0 to -9.2); FEF25-75% (-12.4%; [...] -5.5), particularly in asthmatic women (n = 183): FVC -4.4% (-9.6 to +1.1); FEV1: -8.7% (-14.5 to -2.5); FEF25-75%: -20.8% (-32 to -7.6), where duration of ETS exposure at work was associated with lung function
Status of soil-transmitted helminth infections in schoolchildren in Laguna Province, the Philippines: determined by parasitological and molecular... (Publications)
least one type of STH infection (33.8% by KK vs. 78.3% by qPCR), Ascaris lumbricoides (20.5% by KK vs. 60.8% by qPCR) and Trichuris trichiura (23.6% by KK vs. 38.8% by qPCR). Considering the combined results [...] infections with Ancylostoma spp. (4.6%), Necator americanus (2.3%), and Strongyloides stercoralis (0.8%) that were missed by KK. CONCLUSION/SIGNIFICANCE: qPCR may provide new and important diagnostic information
