Glutathione S-transferase genotypes modify lung function decline in the general population: SAPALDIA cohort study (Publications)
The additional mean annual decline in FEV1 in men with GSTT1 and concurrent GSTM1 gene deletion was -8.3 ml/yr (95% confidence interval: -12.6 to -3.9) relative to men without these gene deletions. The GSTT1
Associations of daily walking activity with biomarkers related to cardiac distress in patients with chronic obstructive pulmonary disease (Publications)
cardiac biomarkers in patients with COPD. Methods: One hundred and five patients with COPD (66.1 +/- 8.7 years of age) were prospectively analyzed. Daily walking activity was measured by means of accelerometry
Farm exposure and time trends in early childhood may influence DNA methylation in genes related to asthma and allergy (Publications)
001). Changes in methylation over time occurred in 15 gene regions (lowest P-value (IL13) = 1.57*10(-8) ). Interestingly, these differences clustered in the genes highly associated with asthma (ORMDL family)
Endogenous sex hormones and incident fracture risk in older men: the Dubbo Osteoporosis Epidemiology Study (Publications)
60 years had been observed between January 1989 and December 2005, with the median duration being 5.8 years (up to 13 years). Clinical risk factors, including bone mineral density and lifestyle factors
Impact of a national HIV voluntary counselling and testing (VCT) campaign on VCT in a rural hospital in Tanzania (Publications)
(OR 1.61, 95%CI 1.21-2.15, P = 0.001) or divorced/widowed compared to single (OR 4.58, 95% CI 3.00-8.12, P < 0.001). Conclusions Our results suggest that the National VCT Campaign raised awareness and
Availability and costs of antiepileptic drugs and quality of phenobarbital in Vientiane municipality, Lao PDR (Publications)
indicated amount. RESULTS: 66 pharmacies were enrolled (13 and 45 of categories I and II, respectively, and 8 hospital pharmacies). Six generics of AEDs were found (phenobarbital, phenytoin, valproic acid, clonazepam
PTEN expression is a strong predictor of survival in mesothelioma patients (Publications)
significantly longer (log rank test p=0.0001) in patients with PTEN expression (15.5 months; 95% CI: 3.8; 27.2 vs 9.7 months; 95% CI: 7.9; 11.7). Cox regression analysis revealed an association between PTEN
A community study of the effect of particulate matter on blood measures of inflammation and thrombosis in an elderly population (Publications)
METHODS: We measured these blood markers in 47 elderly individuals with (23) and without (16 COPD and 8 healthy) cardiovascular disease (CVD) on 2 or 3 mornings over a 5 or 10-day period between February
Tribendimidine: a promising, safe and broad-spectrum anthelmintic agent from China (Publications)
or with N. americanus and Ancylostoma duodenalis, resulted in cure rates of 85.7% (132/154) and 89.8% (53/59), respectively. In comparison, a single oral dose of 400 mg albendazole resulted in significantly
Rice irrigation and schistosomiasis in savannah and forest areas of Côte d'Ivoire (Publications)
harvest per year and (R0) absence of rice growing. In the savannah zone, S. haematobium prevalence was 4.8%, 2.3% and 0.7% and S. mansoni prevalence was 16.1%, 11.9% and 2.1% in R2, R1 and R0, respectively.