The epidemiology of multiple <em>Plasmodium falciparum</em> infections. 8. Effect of iron supplementation and malaria prophylaxis in infants on... (Publications)
conditions of intense transmission, all samples of P. falciparum obtained from children aged 5 and 8 months were genotyped by polymerase chain reaction-restriction fragment length polymorphism analysis
8-O-methyldioncophyllinol B and revised structures of other 7,6'- coupled naphthylisoquinoline alkaloids from <em>Triphyophyllum peltatum... (Publications)
The isolation and structural elucidation of a new naphthylisoquinoline alkaloid, 8-O-methyldioncophyllinol B, from Triphyophyllum peltatum (Hutch. et Dalz.) Airy Shaw (Dioncophyllaceae) is described, together [...] structures of other 'B-type' compounds previously misidentified as dioncophylline D, dioncophyllinol D, and 8-O- methyldioncophylline D. All of the presently described structures are 7,6'-coupled and thus have [...] quinoline alkaloids. This is in contrast to the initially...
Ancistrotanzanine A, the first 5,3'-coupled naphthylisoquinoline alkaloid, and two further, 5,8'-linked related compounds from the newly described... (Publications)
unprecedented 5,3'-coupling type between the naphthalene and isoquinoline portions, while 6 and 7 are 5,8'-coupled. The structures of the compounds were determined by spectroscopic, chemical, and chiroptical
Comparative antimalarial activities of six pairs of 1,2,4,5-tetraoxanes (peroxide dimers) and 1,2,4,5,7,8-hexaoxonanes (peroxide trimers) (Publications)
Six tetraoxanes had 50% inhibitory concentrations in the range of 10 to 100 ng/ml against Plasmodium falciparum, whereas the corresponding hexaoxonanes had minimal antimalarial activity. The lack of i
Cytokeratin 8 is a suitable epidermal marker during zebrafish development (Publications)
We have cloned and characterized the zebrafish (Danio rerio) homologous cytokeratin 8 (zf-K8) cDNA. This cytokeratin belongs to the gene family of intermediate filaments and it is a component of the c [...] intestinal progenitors. During later embryonic stage zf-K8 mRNA is strongly expressed in the developing pectoral fin. In adult zebrafish, the zf-K8 gene is not only expressed in simple epithelia such as [...] expression analysis during embryonic development and at adult stages presented here...
Zebrafish keratin 8 is expressed at high levels in the epidermis of regenerating caudal fin (Publications)
zebrafish (Danio rerio) homologous cytokeratin 8 cDNA (zfk8) which was described as an epidermal marker during zebrafish development. It has been found that the zfk8 gene is normally expressed in simple epithelia [...] and are mainly expressed in epithelial cells. In several vertebrates it has been shown that keratin 8 is expressed in simple epithelial tissues, some non-epithelial tissue and in hyper-proliferative tissues [...] mature zebrafish. Using whole-mount in situ hybridisation, we show...