Socioeconomic benefit to individuals of achieving 2020 targets for four neglected tropical diseases controlled/eliminated by innovative and... (Publications)
total global productivity gained for the four IDM-NTDs was I$ 23.1 (I$ 15.9 -I$ 34.0) billion in 2011-2020 and I$ 35.9 (I$ 25.0 -I$ 51.9) billion in 2021-2030 (2.5th and 97.5th percentiles in brackets), co [...] corresponding to US$ 10.7 billion (US$ 7.4 -US$ 15.7) and US$ 16.6 billion (US$ 11.6 -US$ 24.0). Reduction in OPPs was I$ 14 billion (US$ 6.7 billion) and I$ 18 billion (US$ 10.4 billion) for the same periods
<em>N</em>-substituted noscapine derivatives as new antiprotozoal agents: synthesis, antiparasitic activity and molecular docking study (Publications)
activity against Trypanosoma brucei rhodesiense with IC50 values between 2.5 and 10.0microM and selectivity index (SI) ranged from 0.8 to 13.2. Eight compounds exhibited activity against Plasmodium falciparum
A weighted genetic risk score of adult glioma susceptibility loci associated with pediatric brain tumor risk (Publications)
adult brain tumors was associated with an increased risk of PBTs (OR 1.25 [95% CI 1.06-1.49], p = 0.009) and 0.3% of the variance in PBTs could be explained by the effect of GRS on the liability scale. This
Assessment of factors related to individuals who were never treated during mass drug administration for lymphatic filariasis in Ambon City, Indonesia (Publications)
were respondents working in formal sectors (aOR = 1.75, p = 0.040), living in the catchment area of Waihaong Health Center (aOR = 2.33, p = 0.029), and those perceiving the possibility of adverse events
Breastfeeding following<em> in vitro</em> fertilisation in Switzerland - does mode of conception affect breastfeeding behaviour? (Publications)
the control group could be found over the observational period of 12 months (HR=1.00, 95% CI 0.83-1.20, p=0.984). There was no difference in breastfeeding initiation or duration after gonadotropin stimulated
Synthesis and evaluation of antiparasitic activities of new 4-[5-(4-phenoxyphenyl)-2H-pyrazol-3-yl]morpholine derivatives (Publications)
potency (IC50 of 1.0 and 1.1 microM, respectively). Interestingly, the beta-diketone precursors 1-3 had good antitrypanosomal activity toward the insect stage, with IC50 values of 1.0-3.4 microM. Among
In vitro antiprotozoal activities and cytotoxicity of some selected Cameroonian medicinal plants (Publications)
rhodesiense was the methanolic extract of Albizia zygia (Fabaceae) stem bark with IC50 values of 1.0 mu g/ml and 0.2 mu g/ml, respectively. Five extracts showed IC50 values below 5 mu g/ml against Leishmania
The Washington aerial spray drift study: assessment of off-target organophosphorus insecticide atmospheric movement by plant surface volatilization (Publications)
model were found to be associated to observed field measurement data, with an r(2) = 0.63 the day of the spray and r(2) = 0.67 the day after the spray. The volatilization model however appears to underestimate
Deliberate self-harm and suicide by pesticide ingestion in the Sundarban region, India (Publications)
commonly used means (88.7%). The case fatality of self-harm reported in these hospitals ranged from 6.0% to 50.0% (mean 13.3%; CI, 11.3-15.3). The age group 55-64 years was at highest risk of death, the age group
Antiplasmodial and antitrypanosomal activity of tanshinone-type diterpenoids from <em>Salvia miltiorrhiza</em> (Publications)
against P. FALCIPARUM K1 strain with selectivity indices (SI) from 0.3 to 1.9. IC (50)s against T. BRUCEI RHODESIENSE STIB 900 were from 0.5 microM ( 1, 4) to over 30 microM, and 4 showed the greatest selective
