Efficacy and safety of moxidectin and albendazole compared to ivermectin and albendazole co-administration in adolescents infected with <em>Trichuris... (Publications)
primary objective is to demonstrate non-inferiority of orally co-administered single-dose moxidectin (8 mg)/albendazole (400 mg) compared to orally co-administered single-dose ivermectin (200 microg/kg)/
The double burden of malnutrition and dietary patterns in rural Central Java, Indonesia (Publications)
in analysis. Double burden of malnutrition was prevalent whereby 32.3% of children were stunted, 68.8% of women 35–49 years-old were overweight, and 39% of homes were classified as double burden. The NT
Characterization of the population pharmacokinetics of moxidectin in adults infected with <em>Strongyloides stercoralis</em>: support for a fixed-dose... (Publications)
time zero to infinity of 1907 ± 1552 and 2175 ± 1670 ng × h/mL in the 60-70 kg weight group, after 8 mg fixed- or weight-based dosing, respectively. CONCLUSION: We describe the first PPK model for moxidectin
Two-target quantitative PCR to predict library composition for shallow shotgun sequencing (Publications)
of sample compositions between 4% and 98% nonhuman reads and observed proportions varied between -18.8% and +19.2% from the expected values. We hope that this easy-to-use assay will help researchers to plan
Comparative palatability of orally disintegrating tablets (ODTs) of praziquantel (L-PZQ and Rac-PZQ) versus current PZQ tablet in African children: a... (Publications)
infection as this was not part of the assessment. Children were stratified according to age group (6-8 years or 9-11 years) and gender, then randomized to receive each formulation in a pre-specified sequence
Towards elimination of mother-to-child transmission of HIV in Rwanda: a nested case-control study of risk factors for transmission (Publications)
[aOR]: 9.25; 95 % Confidence Interval [95 % CI]: 2.12-40.38) and during labour or post-partum (aOR: 8.87; 95 % CI: 1.92-40.88), compared to initiation of ART before pregnancy, increased the risk of MTCT
Pathogens that cause acute febrile illness among children and adolescents in Burkina Faso, Madagascar and Sudan (Publications)
ly. The leading identified pathogen overall was Plasmodium spp., accounting for 47% (25/53), 2.2% (8/364) and 45% (90/198) of AFI at respective sites. In Madagascar, dengue virus was the most prevalent
Comparison of two different semiquantitative urinary dipstick tests with albumin-to-creatinine ratio for screening and classification of albuminuria... (Publications)
51.4%, and 87.9% at cut-offs of 30, 100, and > /=300 mg/dL, and with the Micral-Test((R)) it was 1.8%, 10.5%, and 53.6% at cut-offs of 2, 5, and 10 mg/dL, respectively. Overall, disagreement to KDIGO
Development of a multiplex bead assay for the detection of canine IgG4 antibody responses to Guinea worm (Publications)
samples collected 1-2 months apart, the DUF148/GST multiplex assay could identify infected dogs 4-8 months before GW emergence.
Capture-based enrichment of <em>Theileria parva </em>DNA enables full genome assembly of first buffalo-derived strain and reveals exceptional... (Publications)
cattle genotypes differ from the reference by ~54K single nucleotide polymorphisms (SNPs) throughout the 8.31 Mb genome, an average of 6.5 SNPs/kb. We report the first buffalo-derived T. parva genome, which
