Men benefit more from midlife leisure-time physical activity than women regarding the development of late-life disability - results from the KORA-age... (Publications)
activity and high activity had a protective effect on the occurrence of disability (OR (odds ratio)=0.80 and 0.73), but not on severity (i.e. number of limitations). We observed a strong gender-specific difference
Land use regression models for alkylbenzenes in a Middle Eastern megacity: Tehran Study of Exposure Prediction for Environmental Health Research... (Publications)
emission inventory, and several new others. The final models with R2 values ranging from 0.64 for p-xylene to 0.70 for benzene were mainly driven by traffic-related variables but distance to sewage treatment
Performance of antigen concentration thresholds for attributing fever to malaria among outpatients in Angola (Publications)
When considering HRP2 concentration, the malaria attributable fraction of fever was 0.092 in the Huambo province and 0.39 in Uige. Diagnostic tests detecting HRP2 with levels of detection in the 3,000-10
Association between concurrence of multiple risk factors and under-5 mortality: a pooled analysis of data from demographic and health survey in 61... (Publications)
604,372 under-5 children, 18,166 (3.0%) died at the time of the survey. Unsatisfied family planning needs was the strongest risk factor for U5M (odds ratio [OR]: 2.0, 95% confidence interval [CI]: 1.9-2
Dual strategy to design new agents targeting <em>Schistosoma mansoni</em>: advancing phenotypic and <em>Sm</em>CB1 inhibitors for improved efficacy (Publications)
"SmCB1" approach emerging as the most potent compound. 2h displayed nanomolar inhibition of SmCB1 (K(i) = 0.050 μM) while maintaining selectivity toward human off-target cathepsins. Additionally, the greatly [...] improved efficacy of compound 2h toward S. mansoni adults (86% dead worms at 10 μM, 68% at 1 μM, 35% at 0.1 μM) demonstrates its potential as a new therapeutic agent for schistosomiasis, underlined by its improved
Association between concurrence of multiple risk factors and under-5 mortality: a pooled analysis of data from demographic and health survey in 61... (Publications)
604,372 under-5 children, 18,166 (3.0%) died at the time of the survey. Unsatisfied family planning needs was the strongest risk factor for U5M (odds ratio [OR]: 2.0, 95% confidence interval [CI]: 1.9-2
Dual strategy to design new agents targeting <em>Schistosoma mansoni</em>: advancing phenotypic and <em>Sm</em>CB1 inhibitors for improved efficacy (Publications)
"SmCB1" approach emerging as the most potent compound. 2h displayed nanomolar inhibition of SmCB1 (K(i) = 0.050 μM) while maintaining selectivity toward human off-target cathepsins. Additionally, the greatly [...] improved efficacy of compound 2h toward S. mansoni adults (86% dead worms at 10 μM, 68% at 1 μM, 35% at 0.1 μM) demonstrates its potential as a new therapeutic agent for schistosomiasis, underlined by its improved
Assessment of factors related to individuals who were never treated during mass drug administration for lymphatic filariasis in Ambon City, Indonesia (Publications)
were respondents working in formal sectors (aOR = 1.75, p = 0.040), living in the catchment area of Waihaong Health Center (aOR = 2.33, p = 0.029), and those perceiving the possibility of adverse events
Breastfeeding following<em> in vitro</em> fertilisation in Switzerland - does mode of conception affect breastfeeding behaviour? (Publications)
the control group could be found over the observational period of 12 months (HR=1.00, 95% CI 0.83-1.20, p=0.984). There was no difference in breastfeeding initiation or duration after gonadotropin stimulated
Synthesis and evaluation of antiparasitic activities of new 4-[5-(4-phenoxyphenyl)-2H-pyrazol-3-yl]morpholine derivatives (Publications)
potency (IC50 of 1.0 and 1.1 microM, respectively). Interestingly, the beta-diketone precursors 1-3 had good antitrypanosomal activity toward the insect stage, with IC50 values of 1.0-3.4 microM. Among
