In vitro antiprotozoal activities and cytotoxicity of some selected Cameroonian medicinal plants (Publications)
rhodesiense was the methanolic extract of Albizia zygia (Fabaceae) stem bark with IC50 values of 1.0 mu g/ml and 0.2 mu g/ml, respectively. Five extracts showed IC50 values below 5 mu g/ml against Leishmania
The Washington aerial spray drift study: assessment of off-target organophosphorus insecticide atmospheric movement by plant surface volatilization (Publications)
model were found to be associated to observed field measurement data, with an r(2) = 0.63 the day of the spray and r(2) = 0.67 the day after the spray. The volatilization model however appears to underestimate
Deliberate self-harm and suicide by pesticide ingestion in the Sundarban region, India (Publications)
commonly used means (88.7%). The case fatality of self-harm reported in these hospitals ranged from 6.0% to 50.0% (mean 13.3%; CI, 11.3-15.3). The age group 55-64 years was at highest risk of death, the age group
Antiplasmodial and antitrypanosomal activity of tanshinone-type diterpenoids from <em>Salvia miltiorrhiza</em> (Publications)
against P. FALCIPARUM K1 strain with selectivity indices (SI) from 0.3 to 1.9. IC (50)s against T. BRUCEI RHODESIENSE STIB 900 were from 0.5 microM ( 1, 4) to over 30 microM, and 4 showed the greatest selective
Men benefit more from midlife leisure-time physical activity than women regarding the development of late-life disability - results from the KORA-age... (Publications)
activity and high activity had a protective effect on the occurrence of disability (OR (odds ratio)=0.80 and 0.73), but not on severity (i.e. number of limitations). We observed a strong gender-specific difference
Land use regression models for alkylbenzenes in a Middle Eastern megacity: Tehran Study of Exposure Prediction for Environmental Health Research... (Publications)
emission inventory, and several new others. The final models with R2 values ranging from 0.64 for p-xylene to 0.70 for benzene were mainly driven by traffic-related variables but distance to sewage treatment
Performance of antigen concentration thresholds for attributing fever to malaria among outpatients in Angola (Publications)
When considering HRP2 concentration, the malaria attributable fraction of fever was 0.092 in the Huambo province and 0.39 in Uige. Diagnostic tests detecting HRP2 with levels of detection in the 3,000-10
<em>N</em>-substituted noscapine derivatives as new antiprotozoal agents: synthesis, antiparasitic activity and molecular docking study (Publications)
activity against Trypanosoma brucei rhodesiense with IC50 values between 2.5 and 10.0microM and selectivity index (SI) ranged from 0.8 to 13.2. Eight compounds exhibited activity against Plasmodium falciparum
A weighted genetic risk score of adult glioma susceptibility loci associated with pediatric brain tumor risk (Publications)
adult brain tumors was associated with an increased risk of PBTs (OR 1.25 [95% CI 1.06-1.49], p = 0.009) and 0.3% of the variance in PBTs could be explained by the effect of GRS on the liability scale. This
Global, regional, and national burden of stroke and its risk factors, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021 (Publications)
most common cause of DALYs (160·5 million [147·8-171·6] DALYs; 5·6% [5·0-6·1] of all DALYs). In 2021, there were 93·8 million (89·0-99·3) prevalent and 11·9 million (10·7-13·2) incident strokes. We found [...] al haemorrhage constituted 28·8% (28·3-28·8), and subarachnoid haemorrhage constituted 5·8% (5·7-6·0) of incident strokes. There were substantial increases in DALYs attributable to high BMI (88·2% [53 [...] [2·5-11·6]), lead exposure (6·5% [4·5-11·2]), and diet low in omega-6...
