Effectiveness and cost of an incentive-based intervention on food safety and income in "dibiteries" in Dakar, Senegal (Publications)
in phase 3. The cost of intervention and hygiene improvement was estimated at 67 FCFA ($ 0.12) and 41 FCFA ($ 0.07) / day respectively and did not significantly impact on dibiterie profitability. Incentives [...] ly improved, with only 11.5% showing contamination with any of the bacterial species analysed (p < 0.1). Compared to the control group, only samples from dibiteries in group (b) had significantly reduced
Burden of soil-transmitted helminth infection in pregnant refugees and migrants on the Thailand-Myanmar border: results from a retrospective cohort (Publications)
likely to miscarry when compared to women with negative stool samples (adjusted hazard ratio 0.63, 95% CI 0.48-0.84). STH infections were not significantly associated with stillbirth, preterm birth and born
Safety and immunogenicity of H1/IC31(R), an adjuvanted TB subunit vaccine, in HIV-infected adults with CD4+ lymphocyte counts greater than 350... (Publications)
Local injection site reactions were more common in H1/IC31 versus placebo recipients (65.0% vs. 12.5%, p = 0.015). Solicited systemic and unsolicited adverse events were similar by study arm. The baseline [...] placebo was randomly allocated in a 5ratio1 ratio. The vaccine was administered intramuscularly at day 0 and 56. Safety assessment was based on medical history, clinical examinations, and blood and urine testing
Health-related quality of life among school children with parasitic infections: findings from a national cross-sectional survey in Côte d'Ivoire (Publications)
trichiura prevalences of 75.0%, 17.2%, 5.7%, 3.7%, 1.8%, and 1.3%, respectively. Anemic children showed a significant 1-point reduction in self-rated HrQoL on a scale from 0 to 100, whereas no significant [...] proofed useful, as floor and ceiling effects were negligible, internally consistent (Cronbach's alpha = 0.71), and valid, as revealed by significant negative correlations and associations with children's s
2-Hexadecynoic acid inhibits plasmodial FAS-II enzymes and arrests erythrocytic and liver stage <em>Plasmodium</em> infections (Publications)
88 mug/ml, control drug atovaquone 0.37 ng/ml). 2-HDA showed the best inhibitory activity against the PfFAS-II enzymes PfFabI and PfFabZ with IC(50) values of 0.38 and 0.58 mug/ml (IC(50) control drugs 14
Efficacy and reinfection with soil-transmitted helminths 18-weeks post-treatment with albendazole-ivermectin, albendazole-mebendazole,... (Publications)
albendazole-oxantel pamoate showed a significantly higher efficacy against T. trichiura (CR: 54.0 %, 95 % CI: 43.7-64.0; ERR: 98.6 %, 95 % CI: 97.8-99.2) compared to the other treatment arms. Children treated [...] 37.2 % for T. trichiura (95 % CI: 28.3-46.8), 34.6 % for A. lumbricoides (95 % CI: 27.3-42.3) and 25.0 % for hookworms (95 % CI: 15.5-36.6). CONCLUSION: The moderate reinfection rates with STHs 18 weeks
A multi-country analysis on potential adaptive mechanisms to cold and heat in a changing climate (Publications)
adaptation in each population. RESULTS: Heat-related AFs decreased in all countries (ranging from 0.45-1.66% to 0.15-0.93%, in the first and last 5-year periods, respectively) except in Australia, Ireland and
Association between helminth infections and diabetes mellitus in adults from the Lao People's Democratic Republic: a cross-sectional study (Publications)
(30.5%). We found a positive association between Taenia spp. infections and HbA1c (beta = 0.117; 95% CI: 0.042-0.200) and diabetes mellitus risk (OR = 2.98; 95% CI: 1.10-8.05). No other helminth species
Molecular monitoring of the diversity of human pathogenic malaria species in blood donations on Bioko Island, Equatorial Guinea (Publications)
higher (26%, 52/200). Densities of P. falciparum positive blood donations were ranging from 0.06 to 3707.0 parasites/microL with 79.6% below 100 parasites/microL and therefore not detectable by non-molecular [...] polymerase chain reaction. RESULTS: In comparison to 6.5% (13/200) by rapid diagnostic test and 2.0% (4/200) by microscopy, the proportion of Plasmodium falciparum positive blood donations analysed by
Poor mental health of livestock farmers in Africa: a mixed methods case study from Ghana (Publications)
illnesses in farmers, but positively associated with increasing herd size [F (8,278) = 14.18, p < 0.001, R(2) = 0.29]. CONCLUSIONS: Livestock diseases are the leading cause of losses to livestock farmers, whose [...] evaluated the factors that explained variations in mental wellbeing using general linear models (alpha = 0.05). RESULTS: About 85% (240/287) of the livestock farmers lost cattle within 1 year. Of these, 91%