Predicting complicated appendicitis based on clinical findings: the role of Alvarado and appendicitis inflammatory response scores (Publications)
sensitivity of > 90% to detect complicated appendicitis was > == 5 (sensitivity = 95%, specificity 8.99%). The highest AIR score with a sensitivity of > 90% to detect complicated appendicitis was > ==
Cumulative antibiotic exposure in the first five years of life: estimates for 45 low- and middle-income countries from demographic and health survey... (Publications)
11.6-24.6) in LMICs. Cumulative antibiotic exposure ranged from 3.7 treatments in Niger (95% CI: 2.8-4.6) to 38.6 treatments in DR Congo (95% CI: 34.7-42.4). A median of 9.0% of antibiotic treatment was
Exposure to ambient air pollution and cognitive decline: results of the prospective Three-City cohort study (Publications)
domain-specific cognitive decline. Results The participants’ (n = 6380) median age was 73.4 years (IQR: 8.0), and 61.5% were women. At baseline, the median MMSE score was 28 (IQR: 3). Global cognition decline
Failure to return pillbox is a predictor of being lost to follow-up among people living with HIV on antiretroviral therapy in rural Tanzania (Publications)
pillbox return than among those who returned their pillbox [30.0%, 95% confidence interval (CI): 26.8-33.2% vs. 19.4%, 95% CI: 17.4-21.6%, respectively, at 24 months (hazard ratio = 1.67, 95% CI: 1.46-1
Rabies burden in Côte d'Ivoire (Publications)
each year [95% CI 16122-30969]. The estimated annual cost of rabies is 40.15 million USD [95% CI 27.8-53.4]. Overall, 99% of the cost was due to premature deaths. The cost of post-exposure prophylaxis was
Dynamics and risk of transmission of bovine tuberculosis in the emerging dairy regions of Ethiopia (Publications)
survey, consistent with the infection being endemic. The incidence rate was estimated at 3.6 (95% CI 2.8-4.5) and 6.6 (95% CI 3.0-12.6) cases/100 cattle (or herd)-years at the animal- and herd-levels, respectively
Evaluating different storage media for identification of <em>Taenia saginata</em> proglottids using MALDI-TOF mass spectrometry (Publications)
LC–MS grade water; (ii) 0.45% sodium chloride; (iii) 70% ethanol; and (iv) 37% formalin after 2, 4, 6, 8, 12, and 24 weeks of storage. MALDI-TOF MS correctly identified 97.2–99.7% of samples stored in water
Efficacy and safety of moxidectin and albendazole compared to ivermectin and albendazole co-administration in adolescents infected with <em>Trichuris... (Publications)
primary objective is to demonstrate non-inferiority of orally co-administered single-dose moxidectin (8 mg)/albendazole (400 mg) compared to orally co-administered single-dose ivermectin (200 microg/kg)/
The double burden of malnutrition and dietary patterns in rural Central Java, Indonesia (Publications)
in analysis. Double burden of malnutrition was prevalent whereby 32.3% of children were stunted, 68.8% of women 35–49 years-old were overweight, and 39% of homes were classified as double burden. The NT
Characterization of the population pharmacokinetics of moxidectin in adults infected with <em>Strongyloides stercoralis</em>: support for a fixed-dose... (Publications)
time zero to infinity of 1907 ± 1552 and 2175 ± 1670 ng × h/mL in the 60-70 kg weight group, after 8 mg fixed- or weight-based dosing, respectively. CONCLUSION: We describe the first PPK model for moxidectin