Two-target quantitative PCR to predict library composition for shallow shotgun sequencing (Publications)
of sample compositions between 4% and 98% nonhuman reads and observed proportions varied between -18.8% and +19.2% from the expected values. We hope that this easy-to-use assay will help researchers to plan
Comparative palatability of orally disintegrating tablets (ODTs) of praziquantel (L-PZQ and Rac-PZQ) versus current PZQ tablet in African children: a... (Publications)
infection as this was not part of the assessment. Children were stratified according to age group (6-8 years or 9-11 years) and gender, then randomized to receive each formulation in a pre-specified sequence
Towards elimination of mother-to-child transmission of HIV in Rwanda: a nested case-control study of risk factors for transmission (Publications)
[aOR]: 9.25; 95 % Confidence Interval [95 % CI]: 2.12-40.38) and during labour or post-partum (aOR: 8.87; 95 % CI: 1.92-40.88), compared to initiation of ART before pregnancy, increased the risk of MTCT
Pathogens that cause acute febrile illness among children and adolescents in Burkina Faso, Madagascar and Sudan (Publications)
ly. The leading identified pathogen overall was Plasmodium spp., accounting for 47% (25/53), 2.2% (8/364) and 45% (90/198) of AFI at respective sites. In Madagascar, dengue virus was the most prevalent
Comparison of two different semiquantitative urinary dipstick tests with albumin-to-creatinine ratio for screening and classification of albuminuria... (Publications)
51.4%, and 87.9% at cut-offs of 30, 100, and > /=300 mg/dL, and with the Micral-Test((R)) it was 1.8%, 10.5%, and 53.6% at cut-offs of 2, 5, and 10 mg/dL, respectively. Overall, disagreement to KDIGO
Capture-based enrichment of <em>Theileria parva </em>DNA enables full genome assembly of first buffalo-derived strain and reveals exceptional... (Publications)
cattle genotypes differ from the reference by ~54K single nucleotide polymorphisms (SNPs) throughout the 8.31 Mb genome, an average of 6.5 SNPs/kb. We report the first buffalo-derived T. parva genome, which
Development of a multiplex bead assay for the detection of canine IgG4 antibody responses to Guinea worm (Publications)
samples collected 1-2 months apart, the DUF148/GST multiplex assay could identify infected dogs 4-8 months before GW emergence.
An in-depth report of quality control on Kato-Katz and data entry in four clinical trials evaluating the efficacy of albendazole against... (Publications)
Tanzania, where we noted a 2.2 percentage point increase in MHI infections (pre-QC: 1.6% vs. post-QC: 3.8%). There was a 100% agreement in the classification of drug efficacy of albendazole against STH between
Efficacy, metabolism and pharmacokinetics of Ro 15-5458, a forgotten schistosomicidal 9-acridanone hydrazone (Publications)
the presence of microsomes or whole hepatocytes. The maximum plasma concentration was approximately 8.13 mug/mL 3 h after a 50 mg/kg oral dose and the half-life was approximately 4.9 h. CONCLUSIONS: Ro
Protection from childhood asthma and allergy in Alpine farm environments - the GABRIEL Advanced Studies (Publications)
children answered a recruiting questionnaire (phase I). In phase II a stratified random subsample of 8,419 children answered a detailed questionnaire on farming environment. Blood samples and specific IgE