Alcohol use and depression: link with adherence and viral suppression in adult patients on antiretroviral therapy in rural Lesotho, Southern Africa: a... (Publications)
were hazardous drinkers (men: 10.7 %, women: 4.4 %, p < 0.001). The prevalence of depressive symptoms was 28.8 % (men 20.2 %, women 32.7 %, p < 0.001). Both alcohol consumption (adjusted odds-ratio: 2.09
The influence of meteorological factors and atmospheric pollutants on the risk of preterm birth (Publications)
factors were estimated using adjusted discrete-time Cox models. The frequency of preterm birth was 5.0%. Preterm birth risk tended to increase with first-trimester average atmospheric pressure (odds ratio [...] temperature in the -5 degrees C to 15 degrees C range, with a plateau afterwards (spline coding, P = 0.08). No evidence of adverse association with atmospheric pollutants was observed. Our study lends support
1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function (Publications)
Genomes reference panel. Using pathway analysis, we identified 39 significant (FDR < 0.05) genes and 127 significantly (FDR < 0.05) enriched gene sets, which were missed by our previous analyses. Among those
The migration-related language barrier and professional interpreter use in primary health care in Switzerland (Publications)
in this nation-wide cross-sectional study face relevant language barriers at least once a year, 30.0% even once a week. Using family members and friends for translations is reported as the most frequent [...] language barrier (60.1% report it for more than 50% of encounters), followed by "using gestures" (32.0%) or just accepting the insufficient communication (22.9%). Minors interpret frequently (frequent use:
Body weight changes in people with HIV starting dolutegravir versus efavirenz-based regimens in a large cohort in rural Tanzania (Publications)
7-5.5) in the dolutegravir versus 4.0 kg (95%CI 3.7-4.4) in the efavirenz group. The weight gain difference between treatment groups was high in men (1.7 kg (95%CI 0.8-2.6; p
Risk, attributable fraction and attributable number of cause-specific heat-related emergency hospital admissions in Switzerland (Publications)
attributed 31,387 (95% confidence interval: 21,567-40,408) EHAs to above-optimal temperatures, 1.1% (0.7%-1.4%) of the total. Extreme temperatures increased the EHA risk for mental, infectious and neurological [...] EHA risk generally increased with age, we also found high RRs for infectious diseases in children (0-15 years) and AKI in young adults (15-64 years). CONCLUSION: Hot weather increases the EHA risk in
Body weight changes in people with HIV starting dolutegravir versus efavirenz-based regimens in a large cohort in rural Tanzania (Publications)
7-5.5] in the dolutegravir versus 4.0 kg (95% CI 3.7-4.4) in the efavirenz group. The weight gain difference between treatment groups was high in men (1.7 kg (95% CI 0.8-2.6; P
A digital health algorithm to guide antibiotic prescription in pediatric outpatient care: a cluster randomized controlled trial (Publications)
was noninferior in ePOCT+ facilities compared to usual care facilities (adjusted relative risk 0.97, 95% CI 0.85 to 1.10). There was no difference in the secondary safety outcomes of death and nonreferred
COVID-19 screening in low resource settings using artificial intelligence for chest radiographs and point-of-care blood tests (Publications)
participants were included. In our cohort, AI for CXR images was a poor predictor of COVID-19 (AUC = 0.60), since the majority of positive cases had mild symptoms and no visible pneumonia in the lungs. AI [...] blood cell counts (WBC), or a combination of WBC and C-Reactive Protein (CRP) both achieved an AUC of 0.74 with a suggested optimal cut-off point at 83% sensitivity and 63% specificity. The antigen-RDT tests
Revised EU and WHO air quality thresholds: where does Europe stand? (Publications)
exposed to concentrations above the WHO annual thresholds was estimated at 62.5% (54.0, 70.9%) and at 29.6 (21.9, 37.0%) above the EU values, whereas for NO2, the estimates were at 67.4% (57.9, 75.8%) and
