Safety and immunogenicity of radiation-attenuated PfSPZ vaccine in equatoguinean infants, children, and adults (Publications)
differences in solicited adverse events (AEs) between vaccinees and controls in any age group (P > /= 0.17). There were no significant differences between vaccinees and controls with respect to the rates [...] Development of antibodies to P. falciparum circumsporozoite protein occurred in 67/69 vaccinees (97%) and 0/15 controls. Median antibody levels were highest in infants and 1-5-year-olds and declined progressively
Laboratory-based efficacy evaluation of <em>Bacillus thuringiensis</em> var. <em>israelensis </em>and temephos larvicides against larvae of... (Publications)
larvae of invasive An. stephensi. METHODS: The diagnostic doses of two larvicides, temephos (0.25 ml/l) and Bti (0.05 mg/l) were tested in the laboratory against the immature stages (late third to early fourth
Physical activity, sedentary behaviour, weight status, and body composition among South African primary schoolchildren (Publications)
(ps < 0.001). Lower MVPA was associated with a higher likelihood of being overweight/obese, higher relative body fat, and lower relative fat-free mass, bone mass, muscle mass, and body water (ps < 0.001)
Care seeking and treatment of febrile children with and without danger signs of severe disease in northern Uganda: results from three household... (Publications)
compared with those without danger signs (adjusted odds ratio: 1.6, 95% confidence interval: 1.2-2.0; P < 0.01). In the total population studied, care seeking in the public sector was 26% and similar to care
Similar but different: integrated phylogenetic analysis of Austrian and Swiss HIV-1 sequences reveal differences in transmission patterns of the local... (Publications)
patients were in domestic cherries, 8.3% in international cherries, and 7.0% in SHCS/AHIVCOS cherries. Similarly, in the SHCS, 43.0% of the patients were in domestic cherries, 8.2% in international cherries
Posttraumatic stress disorder predicts poor health-related quality of life in cardiac patients in Palestine (Publications)
moderate-to-high PTSD symptoms among 1022 patients at baseline was 27∙0%. Patients with PTSD symptoms reported an approximate 20∙0% lower HRQL at follow-up. The PTSD and HRQL relationship was largely mediated
Modelling to quantify the likelihood that local elimination of transmission has occurred using routine <em>gambiense </em>human African... (Publications)
certainty that EOT has been met there (99.0% for Model S and 88.5% for Model W), and this could be higher with 50% coverage screening that year (99.1% for Model S and 94.0% for Model W). CONCLUSIONS: We demonstrate
Application of the Parent Attitudes about Childhood Vaccines (PACV) survey in three national languages in Switzerland: exploratory factor analysis and... (Publications)
extracted three sub-domains in German and French and four sub-domains in Italian. Cronbach's alpha was > 0.8 across the three languages, and MSA produced a 13-item German, 14-item French, and 11-item Italian [...] EFA and MSA of the short version PACV extracted a single factor and scale with Cronbach's alpha > 0.7 in all three language versions. VH was significantly associated with non-timely receipt of the first
Who is best to test? A systematic review of chlamydia infections in Switzerland (Publications)
literature search generated 108 hits, and nine studies were included. Chlamydia prevalence ranged between 0.8 and 12.8%. Most frequently affected were undocumented women undergoing voluntary termination of pregnancy [...] HIV-positive men who have sex with men (10.9%, 95% CI: 9.2-17.6), and adult offenders (6.5%, 95% CI: 3.2-9.0). Systematic screening was suggested for the first two risk groups and women suffering a miscarriage
Elucidation of the<em> in vitro</em> and <em>in vivo</em> activities of bridged 1,2,4-trioxolanes, bridged 1,2,4,5-tetraoxanes, tricyclic... (Publications)
monoperoxides, trioxolanes, and tetraoxanes revealed the highest in vitro activity against NTS (IC50s 0.4-20.2µM) and adult schistosomes (IC50s 1.8-22.8µM). Tetraoxanes showed higher cytotoxicity than an [...] observed for two trioxolanes, which showed moderate worm burden reductions (WBR) of 44.3% and 42.9% (p> 0.05). Complexation of the compounds with ß-cyclodextrin with the aim to improve solubility and gastr