Use of whole genome sequencing to determine the microevolution of <em>Mycobacterium tuberculosis</em> during an outbreak (Publications)
link. The outbreak strain resulted in 5 bacterial variants originating from the index case A1 with 0-2 mutations per transmission event that resulted in a secondary case. CONCLUSIONS: Whole genome sequencing [...] tuberculosis enabled us to identify microevolutionary events observable during transmission, to determine 0-2 single nucleotide polymorphisms per transmission event that resulted in a secondary case, and to identify
Risk of latent tuberculosis infection in children living in households with tuberculosis patients: a cross sectional survey in remote northern Lao... (Publications)
Laos (289 per 100,000). We evaluated the risk of latent tuberculosis infection (LTBI) among children (0-15 years) living with tuberculosis patients in rural northern Laos. METHODS: In a cross sectional survey [...] 148 contact-children received prophylaxis, one had cervical tuberculosis; the risk for LTBI was 31.0%. Awareness of the infectiousness of tuberculosis was low among patients (31%) and their contacts (31%)
Exposition environnementale à des déchets contenant du mercaptan, des hydrocarbures aromatiques et de l'hydrogène sulfuré (Abidjan) (Publications)
study also showed that the radius of the zone affected varied from 0.4 km to 3 km, much higher than the officially defined and accepted 0.2-km radius. Finally, it showed that several environmental factors
Anémie dans une école du Cambodge rural: détection, prévalence et liens avec les parasitoses intestinales et la malnutrition (Publications)
appeared inaccurate. Anaemia was independently associated with Ancylostoma carriage (p = 0.05), and stunting (p = 0.01), which prevalences were 54% et 40% respectively; and this, despite a mebendazole 500
A randomized trial comparing two different approaches of pacemaker selection (Publications)
frequently with SA (51%) compared to TA (37%, P = 0.045). There was no difference regarding all single secondary endpoints. Hardware costs were reduced by 15% (P < 0.0001). CONCLUSION: In long-term follow-up,
Cleavage of trypanosome surface glycoproteins by alkaline trypsin-like enzyme(s) in the midgut of <em>Glossina morsitans</em> (Publications)
h after their first bloodmeal, a pH gradient from the proventriculus (pH 10.6+/-0.6) to the posterior midgut (pH 7.9+/-0.4) was observed
Use of B-type natriuretic peptide in the management of acute dyspnea in patients with pulmonary disease (Publications)
for hospital admission (81% vs 91%, P = .034). Median time to discharge was 9.0 days in the BNP group as compared with 12.0 days (P = .001) in the clinical group. Median total cost of treatment was $4841
The antiprotozoal activity of methylated flavonoids from <em>Ageratum conyzoides</em> L (Publications)
of illnesses including sleeping sickness, was recently found to exhibit a prominent activity (IC(50)=0.78 microg/mL) against bloodstream forms of Trypanosoma brucei rhodesiense, the etiologic agent of East [...] donovani (Kala-Azar, IC(50)=3.4 microg/mL) as well as Plasmodium falciparum (Malaria tropica, IC(50)=8.0 microg/mL). In the current study, we sought for potentially active constituents of Ageratum conyzoides
Efficacy of the cyclooctadepsipeptide PF1022A against <em>Heligmosomoides bakeri in vitro</em> and <em>in vivo</em> (Publications)
(48-100%), while slightly lower activities were observed with ivermectin (20-92%) and albendazole (0-87%) at 1-100 mug/ml. PF1022A and levamisole significantly inhibited motility and egg release of adult [...] worm burden reductions were achieved with PF1022A, levamisole and ivermectin in vivo. For example, at 0.125 mg/kg PF1022A a worm burden reduction of 91.8% was observed. The use of drug combinations did not
Expression of the extracellular matrix protein periostin in liver tumours and bile duct carcinomas (Publications)
in tumour cells was significantly associated with a higher tumour grade (P < 0.05) and hepatitis B virus infection (P = 0.007). Importantly, there was no strong periostin expression in benign liver tumours
