IGF-1, IGF-2 and IGFBP-3 in prediagnostic serum: association with colorectal cancer in a cohort of Chinese men in Shanghai (Publications)
showed odds ratios of 2.74 (95% Cl = 1.67-4.50; 2-sided P for trend = 0.0008) and 2.85 (95% Cl = 1.69-4.81; 2-sided P for trend = 0.01), respectively. Our data thus suggest that circulating IGF-2 and IGFBP-3
Exposure to farming in early life and development of asthma and allergy: a cross-sectional survey (Publications)
exposure to stables until age 5 years was associated with the lowest frequencies of asthma (0.8% 1/122), hay fever (0.8% 1), and atopic sensitisation (8.2% 10). INTERPRETATION: Long-term and early-life exposure
Mortality from neurodegenerative disease and exposure to extremely low-frequency magnetic fields: 31 years of observations on Swiss railway employees (Publications)
drivers compared to station masters was 1.96 [95% confidence interval (CI) = 0.98-3.92] for senile dementia and 3.15 (95% CI = 0.90-11.04) for Alzheimer's disease. For every 10 microT years of cumulative
Short-term effects of carbon monoxide on mortality: an analysis within the APHEA project (Publications)
of CO levels was associated with a 1.20% [95% confidence interval (CI), 0.63-1.77%] increase in total deaths and a 1.25% (95% CI, 0.30-2.21%) increase in cardiovascular deaths. There was indication of c
Rapid diagnostic test-based management of malaria: an effectiveness study in Papua New Guinean infants with <em>Plasmodium falciparum</em> and... (Publications)
children reattended the clinic within 7 days for fever, of whom 29 (0.7%) were parasitemic by RDT or microscopy. Of children who reattended, 24 (0.7%) presented with a severe illness: 2 had lower respiratory
Comparative study of the effects of artemether and artesunate on juvenile and adult<em> Schistosoma mansoni</em> in experimentally infected mice (Publications)
(P < 0.05). Total concentrations of 600 or 800 mg/kg artemether, administered over 2 or 4 consecutive days to mice with adult S. mansoni, reduced the worm burden significantly by 46-51% (P < 0.05). The
Exposure to endotoxin or other bacterial components might protect against the development of atopy (Publications)
higher indoors in dust from kitchen floors (143 EU/mg vs 39 EU/mg, P < 0.001) and children's mattresses (49479 EU/m2 vs 9383 EU/m2, P < 0.001) as compared to control children from nonfarming families. In addition
Cold extremities and difficulties initiating sleep: evidence of co-morbidity from a random sample of a Swiss urban population (Publications)
to complete a questionnaire on sleep behavior and TDCE (response rate: 72.3% in women, n = 1001; 60.0% in men, n = 809). Values of DIS and TDCE were based on questionnaire-derived scores. In addition, TDCE [...] prevalence rates of DIS were only slightly higher in women in comparison to men (9.3% versus 6.7%, P < 0.1). Irrespective of gender, each seventh subject complaining of TDCE had concomitant DIS and the relative
Evaluation of Turkish seaweeds for antiprotozoal, antimycobacterial and cytotoxic activities (Publications)
active against T. brucei rhodesiense; the Dasya pedicellata extract was the most potent (IC(50) value 0.37 microg/mL). The same extract also weakly inhibited the growth of T. cruzi (IC(50) 62.02 microg/mL) [...] exhibited antiplasmodial potential and the most potent extracts were those from D. pedicellata (IC(50) 0.38 microg/mL), Codium bursa (IC(50) 1.38 microg/mL) and Caulerpa rasemosa (IC(50) 3.12 microg/mL). One
Synthesis and antiparasitic activity of new bis-arylimidamides: DB766 analogs modfied in the terminal groups (Publications)
y). Three compounds (7g, 7i, 7j) with thiazole replacing the pyridine rings gave low micromolar (0.17-0.3 µM) IC50 values versus L. amazonensis, however only 7g exhibited an acceptable selectivity index