Vaccines safety; effect of supervision or SMS on reporting rates of adverse events following immunization (AEFI) with meningits vaccine... (Publications)
The incidence rate of reported AEFI per 100 health facility per week was 20.0 (15.9-24.1) in the SMS group, 40.2 (34.4-46.0) in supervision group and 13.6 (10.1-16.9) in the control group. Supervision
Seroprevalence of Rift Valley fever, Q fever, and brucellosis in ruminants on the southeastern shore of Lake Chad (Publications)
confidence interval [CI] 34.2-41.3) in cattle, 18.8% (95% CI 12.3-25.2) in goats, and 10.8% (95% CI 3.0-18.5) in sheep. For brucellosis and Q fever, only cattle samples from islands were analyzed. For Q fever [...] prevalence of 5.7% (95% CI 3.8-7.6), and ELISA showed 11.9% (95% CI 9.3-14.6) with a kappa value of 0.53 showing a moderate agreement between the two tests. This study confirms the presence of the three
Seroprevalence survey of brucellosis among rural people in Mongolia (Publications)
enrolled in the study. The seroprevalence of Brucella spp. was 11.1% (95% confidence interval [CI]: 10.0-12.1), ranging between 2.3% and 22.6% in the eight provinces; 39.2% (n = 609) of nomadic camps had at [...] (adjusted odds ratio [AOR] = 6.9, 95% CI = 5.1-8.7) and being a veterinarian (AOR = 2.8, 95% CI = 1.5-5.0). CONCLUSION: Our study confirms that human brucellosis seroprevalence among rural people in Mongolia
Estimating population and livestock density of mobile pastoralists and sedentary settlements in the south-eastern Lake Chad area (Publications)
of the dry season and 34 (in 2011) and 30 (in 2012) camps at the end of the dry season. A mean of 64.0 people per km2 (95% confidence interval, 20.3-107.8) were estimated to live in sedentary villages. In [...] the beginning and 17.5 people per km2 at the end of the dry season. We recorded per km2 on average 21.0 cattle and 31.6 small ruminants in the sedentary villages and 66.1 cattle and 102.5 small ruminants
Investigation of indolglyoxamide and indolacetamide analogues of polyamines as antimalarial and antitrypanosomal agents (Publications)
was the most potent growth inhibitor of T. brucei (IC50 0.18 muM) identified in the study: it, however, also exhibited poor selectivity (L6 IC50 6.0 muM). There was no apparent correlation between antimalarial
Synthesis and biological evaluation of organoruthenium complexes with azole antifungal agents. First crystal structure of a tioconazole metal complex (Publications)
increasing number of ligands. However at 0.5 mM concentrations all tris-azole complexes statistically significantly reduced the radial growth rate, and also at 0.01 mM concentrations the monoazole complexes
Discovery of antischistosomal drug leads based on tetraazamacrocyclic derivatives and their metal complexes (Publications)
adult worms. Against NTS, all 5 compounds showed IC50 values comparable to that of standard drug PZQ (0.87 to 9.65 muM vs 2.20 muM for PZQ). Three of these, which are bisquinoline derivative of cyclen and [...] and Mn2+-complexes, showed micromolar IC50 values (1.62 muM, 1.34 muM and 4.12 muM, respectively vs 0.10 muM for PZQ) against adult worms. In vivo, the worm burden reductions were 12.3%, 88.4% and 74.8%
Varicella seroprevalence in individuals with a negative or unknown varicella history - results from a large travel clinic in Switzerland between 2008... (Publications)
40 years were significantly more often seronegative (9.5%) than those aged 40 years and above (6.0%, p = 0.049). Seropositivity was associated with nationality. The percentage of seropositives increased
The burden of leprosy in Cameroon: fifteen years into the post-elimination era (Publications)
achieved leprosy elimination in 2000, registering a prevalence rate of 0.94/10,000 population. The prevalence rate dropped further to reach 0.20/10,000 population (78% reduction) in 2014. Similarly, the new
Anti-trypanosomatid elemanolide sesquiterpene lactones from<em> Vernonia lasiopus </em>O. Hoffm (Publications)
dichloromethane extract was found to be particularly active against Trypanosoma brucei rhodesiense (IC50 = 0.17 microg/mL). Bioassay-guided chromatographic fractionation of the dichloromethane extract led to the [...] line). Vernolepin, the main component in the extract, was also the most potent with an IC50 value of 0.05 microg/mL against T.b. rhodesiense trypomastigotes. This compound showed a selectivity index of 14
