destroying the face. It predominantly affects children aged 2 to 6 years living in extreme poverty in Africa, Asia and Latin America. The World Health Organisation (WHO) once estimated that 140,000 children [...] children are affected yearly by noma, with a prevalence of 770,000 survivors worldwide. The disease leads to the decay of the skin, muscles and bones in the face. Survivors face stigma due to severe facial d [...] findings from the review indicated that the high focality of data in the...
Global, regional, and national age-sex specific mortality for 264 causes of death, 1980-2016: a systematic analysis for the Global Burden of Disease... (Publications)
sed rates of deaths from injuries decreased but total numbers varied little. In 2016, the three leading global causes of death in children under-5 were lower respiratory infections, neonatal preterm birth [...] deaths in ages 90-94 years and a 210% (208-212) increase in deaths older than age 95 years. The ten leading causes by rates of age-standardised YLL significantly decreased from 2006 to 2016 (median annualised [...] for all other causes was lower (a decrease of 1.59%) during the same...
Global, regional, and national age-sex specific mortality for 264 causes of death, 1980-2016: a systematic analysis for the Global Burden of Disease... (Publications)
sed rates of deaths from injuries decreased but total numbers varied little. In 2016, the three leading global causes of death in children under-5 were lower respiratory infections, neonatal preterm birth [...] deaths in ages 90-94 years and a 210% (208-212) increase in deaths older than age 95 years. The ten leading causes by rates of age-standardised YLL significantly decreased from 2006 to 2016 (median annualised [...] for all other causes was lower (a decrease of 1.59%) during the same...
million people are at risk of schistosomiasis. Of the 250 million infected people, 200 million live in Africa. Infection occurs when infective larvae released from freshwater snails penetrate the skin of humans [...] rise to a complex chronic intestinal or urogenital disease. When left untreated, schistosomiasis can lead to anaemia, stunted growth, severe damage of organs, and - at worst - death. Challenges in prevention [...] Don McManus, Professor at the QIMR Berghofer Medical Research...
worldwide, including approximately 50 million preschool-aged children, mainly in sub-Saharan Africa. The disease can lead to malnutrition, anemia, stunted growth, and cognitive impairment. In extreme cases, it [...] beginning and has conducted clinical trials in Tanzania, Côte d'Ivoire and Kenya. Today, it is co-leading the programme to introduce the drug to endemic countries. A solution to a critical health challenge [...] reached this critical milestone,” said Peter Steinmann, public...
reservoir. Well-coordinated regional engagement in dog mass vaccination for 10-20 years in Africa and Asia could lead to the elimination of dog rabies at significantly lower cost than the sustained provision [...] have been working on rabies elimination in the sense of One Health together with local partners in Africa for the past 15 years. "Unfortunately, we are currently facing a massive human rabies vaccine shortage
in terms of health outcomes, the quality of health services provided, and user experience. This leads to approximately five million deaths annually from treatable conditions. To assess the system's p [...] systems. Health insurance was found to not necessarily guarantee access to essential services in Africa and Asia. And despite public primary care's intended role, only 4 in 10 people use it as their main [...] studies included Argentina, Colombia, Ethiopia, Greece, India, Italy, Kenya,...
Schistosomes, parasitic blood flukes, cause schistosomiasis, a chronic disease which can lead to anemia, severe damage of organs, reduced growth and, at worst, to death. Infection occurs if schistosomes [...] million people live in areas where the disease is common. More than 90% of cases occur in sub-Saharan Africa (GAHI).Thus, schistosomiasis poses one of the most prevalent tropical diseases with a large impact
extended periods, if not treated. The major burden of BU falls on children in West Africa, where BU is often leading to stigmatization and permanent disabilities. A s transmission pathways and preventable
Re-annotation of the <em>Theileria parva</em> genome refines 53% of the proteome and uncovers essential components of N-glycosylation, a conserved... (Publications)
called East coast fever (ECF), with millions of animals at risk in sub-Saharan East and Southern Africa, the geographic distribution of T. parva. Over a million bovines die each year of ECF, with a tremendous [...] and functional gene annotations across the entire nuclear genome. RESULTS: The re-annotation effort lead to evidence-supported updates in over half of all protein-coding sequence (CDS) predictions, including
