Non-randomized studies using causal-modelling may give different answers than RCTs: a meta-epidemiological study (Publications)
ratios (sROR) 1.04; 95% CI 0.88 to 1.23). The subset of MSM-studies focusing on healthcare decision-making tended to overestimate experimental treatment benefits (sROR 1.44; 95% CI 0.99 to 2.09). CONCLUSION:
Body mass index and weight change are associated with adult lung function trajectories: the prospective ECRHS study (Publications)
equations. RESULTS: In individuals with normal BMI, overweight and obesity at baseline, moderate (0.25-1 kg/year) and high weight gain (> 1 kg/year) during follow-up were associated with accelerated FVC [...] FVC and FEV1 declines. Compared with participants with baseline normal BMI and stable weight (+/-0.25 kg/year), obese individuals with high weight gain during follow-up had -1011 mL (95% CI -1.259 to -763)
Interaction between host genes and <em>Mycobacterium tuberculosis </em>lineage can affect tuberculosis severity: evidence for coevolution? (Publications)
IL12B and TBscore was replicated in two independent cohorts (most significant rs3212227, combined p = 0.0006), supporting previous associations of IL12B with TB susceptibility. We also observed significant [...] nucleotide polymorphism (SNP) in SLC11A1 and the L4-Ugandan lineage in both cohorts (rs17235409, meta p = 0.0002). Interestingly, the presence of the L4-Uganda lineage in the presence of the ancestral human allele
Owner valuation of rabies vaccination of dogs, Chad (Publications)
would have their dogs vaccinated against rabies. Owners would pay approximately 400-700 CFA francs (US $0.78-$1.36)/animal. To vaccinate > or=70% of dogs, and thus interrupt rabies transmission, health officials
Owner valuation of rabies vaccination of dogs, Chad (Publications)
would have their dogs vaccinated against rabies. Owners would pay approximately 400-700 CFA francs (US $0.78-$1.36)/animal. To vaccinate > or=70% of dogs, and thus interrupt rabies transmission, health officials
Hepatitis B and C in Europe: an update from the Global Burden of Disease Study 2019 (Publications)
million (95% uncertainty interval [UI] 1·66 to 2·54) incident cases of acute hepatitis B and 0·49 million (0·42 to 0·57) of hepatitis C in Europe. There were an estimated 8·24 million (7·56 to 8·88) prevalent [...] [-35·75 to -25·03]). A moderate reduction in DALYs was estimated for HCV-related cirrhosis (-6·19% [-0·19 to -12·57]). Only HCV-related liver cancer showed a significant increase in DALYs (10·37% [4·81-16·63])
Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks... (Publications)
[UI] 55·8-58·5) of deaths and 41·6% (40·1-43·0) of DALYs. Risks quantified account for 87·9% (86·5-89·3) of cardiovascular disease DALYs, ranging to a low of 0% for neonatal disorders and neglected tropical [...] most risks, data for exposure were synthesised with a Bayesian meta-regression method, DisMod-MR 2.0, or spatial-temporal Gaussian process regression. Relative risks were based on meta-regressions of published [...] pollution for 5·5 million deaths and 141·5 million DALYs, and high BMI...
Hepatitis B and C in Europe: an update from the Global Burden of Disease Study 2019 (Publications)
million (95% uncertainty interval [UI] 1·66 to 2·54) incident cases of acute hepatitis B and 0·49 million (0·42 to 0·57) of hepatitis C in Europe. There were an estimated 8·24 million (7·56 to 8·88) prevalent [...] [-35·75 to -25·03]). A moderate reduction in DALYs was estimated for HCV-related cirrhosis (-6·19% [-0·19 to -12·57]). Only HCV-related liver cancer showed a significant increase in DALYs (10·37% [4·81-16·63])
Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks... (Publications)
[UI] 55·8-58·5) of deaths and 41·6% (40·1-43·0) of DALYs. Risks quantified account for 87·9% (86·5-89·3) of cardiovascular disease DALYs, ranging to a low of 0% for neonatal disorders and neglected tropical [...] most risks, data for exposure were synthesised with a Bayesian meta-regression method, DisMod-MR 2.0, or spatial-temporal Gaussian process regression. Relative risks were based on meta-regressions of published [...] pollution for 5·5 million deaths and 141·5 million DALYs, and high BMI...
The age profile of respiratory syncytial virus burden in preschool children of low- and middle-income countries: a semi-parametric, meta-regression... (Publications)
incidence, probability of hospitalization, or the probability of in-hospital death (p ≤ 0.01, p = 1, p = 0.86, 0.63, respectively). Our study is limited mainly due to the sparsity of the data, especially
