A genome-wide association study on medulloblastoma (Publications)
medulloblastoma risk with OR in the same direction as in the discovery cohort (ORT = 1.59, pvalidation = 0.02). We also selected seven medulloblastoma predisposition genes for investigation using a candidate [...] association was found for rs201458864 (PALB2, ORT = 3.76, p = 3.2 x 10(-4)) and rs79036813 (PTCH1, ORA = 0.42, p = 2.6 x 10(-3)). CONCLUSION: The results of this study, including a novel potential medulloblastoma
One mean to rule them all? The arithmetic mean based egg reduction rate can be misleading when estimating anthelminthic drug efficacy in clinical... (Publications)
was reached by the Holder mean M0.2, followed by the geometric mean (91%, CI: 85-94). Winsorized and trimmed means showed a rather poor performance (e.g. winsorization with 0.1 cut-off showed 85% agreement
Caregiver depression is associated with hair cortisol in a low-income sample of preschool-aged children (Publications)
with HCC (beta = -0.32, p < .001). The adjusted model, which accounted for child age and sex, showed a positive relationship between caregiver depressive symptoms and HCC (beta = 0.22, p < .01). Caregiver
Engagement in care, viral suppression, drug resistance and reasons for non-engagement after home-based same-day ART initiation in Lesotho: a two-year... (Publications)
arm were in care (absolute difference 5%; 95%CI -6-16; p=0.38) and 57% (78/137) vs 54% (74/137) had documented viral suppression (3%; -9-15; p=0.28). Among 36 participants alive and not in care at 24 months
Investigating the drivers of the spatio-temporal patterns of genetic differences between <em>Plasmodium falciparum</em> malaria infections in Kilifi... (Publications)
mean geographic distance between parent and offspring malaria infections for the base model was 0.5 km (95% CI 0.3-1.5), for a distribution with 68% of distances shorter than the mean. Very short mean distances
Comparison of next-generation portable pollution monitors to measure exposure to PM2.5 from household air pollution in Puno, Peru (Publications)
ECM and 71 UPAS co-locations. Overall, the ECM and the UPAS had similar correlation (ECM rho=0.91 vs. UPAS rho=0.88) and agreement (ECM mean difference of 121.7 microg/m(3) vs. UPAS mean difference of 93
Early target attainment with continuous infusion meropenem and piperacillin/tazobactam and utilization of therapeutic drug monitoring in critically... (Publications)
and 100.7 mg/L (IQR, 64.0-160.2), respectively. Pharmacological target was attained in 95.7% (95% confidence interval [CI], 91.7-98.1) of patients receiving meropenem and 77.0% (95% CI, 62.7-87.9) treated
[Preprint] Clonal expansion of artemisinin-resistant <em>Plasmodium falciparum</em> in Uganda is associated with substandard treatment practices (Publications)
emergence (0% vs 6.2%) of a unique K13 haplotype (C469Y). Post–RAS, this mutation was more frequently observed in patients sampled 28-days after RAS treatment (OR = 3.9, 95% CI 1.7, 9.5, p= 0.002) of whom
Prenatal depression severity and postpartum care utilization in a medicaid population (Publications)
visit compared with women with a severe prenatal depression diagnosis (adjusted odds ratio = 0.88, 95% CI = 0.65-1.19). However, this finding was not statistically significant. Conclusions: Our study did
Evaluation of the diagnostic performance of PanbioTM Abbott SARS-CoV-2 rapid antigen test for the detection of COVID-19 from suspects attending ALERT... (Publications)
patients was 79.4% (95% CI 68.3-90). The Abbot RDT and RT-PCR had a Kappa value of agreement of 0.735 (p < 0.001). These values were acceptable when compared to the WHO's suggested thresholds. CONCLUSION:
