Imidazolopiperazines: lead optimization of the second-generation antimalarial agents (Publications)
compounds by leveraging the outcome of a set of in vitro metabolic identification studies. The optimized 8,8-dimethyl imidazolopiperazine analogues exhibited improved potency, in vitro metabolic stability profile
Imidazolopiperazines: lead optimization of the second-generation antimalarial agents (Publications)
compounds by leveraging the outcome of a set of in vitro metabolic identification studies. The optimized 8,8-dimethyl imidazolopiperazine analogues exhibited improved potency, in vitro metabolic stability profile
Association between intimate partner violence and breastfeeding duration: results from the 2004-2014 pregnancy risk assessment monitoring system (Publications)
outcome, breastfeeding duration, was categorized as never breastfed, breastfed 8 weeks or less, and breastfeed more than 8 weeks. Multinomial logistic regression was used to obtain crude and adjusted odds [...] ( n = 67,667) of women reported never breastfeeding. The odds of discontinuing breastfeeding before 8 weeks were 18% higher among women who reported experiencing abuse 12 months before pregnancy compared
Stability of measured and modelled spatial contrasts in NO2 over time (Publications)
contrasts in outdoor NO(2) in 1999-2000 and 2007. LUR models predicted spatial contrast 8 years in the past (2007 model) and 8 years in the future (1999-2000 model) well. This supports the use of LUR models in [...] modelled spatial contrasts in outdoor nitrogen dioxide (NO(2)) pollution across the Netherlands over 8 years. METHODS: NO(2) measurements were conducted at 40 locations in the Netherlands in 1999-2000. In
Myoelectric activity of the ileum, cecum, proximal loop of the ascending colon, and spiral colon in cows with naturally occurring cecal... (Publications)
occurring cecal dilatation-dislocation (CDD) and compare findings with those in healthy cows. ANIMALS: 8 CDD-affected and 6 healthy control cows. PROCEDURES: Immediately after diagnosis, CDD-affected cows [...] underwent surgery; control cows underwent a similar surgical procedure. Before completion of surgery, 8 bipolar silver electrodes were implanted in the ileum (n = 2), cecum (1), PLAC (1), and spiral colon [...] (4) of each cow. Beginning the day after surgery, intestinal myoelectric...
Representative seroprevalences of brucellosis in humans and livestock in Kyrgyzstan (Publications)
Chuy, and Osh Oblasts. The overall apparent seroprevalences of brucellosis were 8.8% in humans (95% CI 4.5-16.5), 2.8% (95% CI 1.6-4.9%) in cattle, 3.3% (95% CI 1.5-6.9%) in sheep, and 2.5% (95% CI 1
Exposure to farming in early life and development of asthma and allergy: a cross-sectional survey (Publications)
until age 5 years was associated with the lowest frequencies of asthma (0.8% 1/122), hay fever (0.8% 1), and atopic sensitisation (8.2% 10). INTERPRETATION: Long-term and early-life exposure to stables and
Psychiatric disorders, suicidality, and personality among young men by sexual orientation (Publications)
10.2% fulfilled diagnostic criteria for major depression in the past 2weeks, 10.8% for ADHD in the past 12months, 13.8% for lifetime anti-social personality disorder (ASPD), and 6.0% attempted suicide [...] adjusting (AOR) for personality traits, their odds ratios (OR) for major depression (OR=4.78, 95% CI 2.81-8.14; AOR=1.46, 95% CI 0.80-2.65) and ADHD (OR=2.17, 95% CI=1.31-3.58; AOR=1.00, 95% CI 0.58-1.75) lost
Incidence and predictors of immune reconstitution inflammatory syndrome in a rural area of Mozambique (Publications)
ART initiation (IQR 35.5-93.5). Twenty-five cases (69.4%) were "unmasking", 10 (27.8%) were "paradoxical", and 1 (2.8%) developed a paradoxical worsening followed by the unmasking of another condition [...] condition. Systemic OI (OI-IRIS) accounted for 47% (17/36) of IRIS cases, predominantly of KS (8 cases) and TB (6 cases) IRIS. Mucocutaneous IRIS manifestations (MC-IRIS) accounted for 53% (19/36) of IRIS events
Association between intimate partner violence and breastfeeding duration: results from the 2004-2014 pregnancy risk assessment monitoring system (Publications)
outcome, breastfeeding duration, was categorized as never breastfed, breastfed 8 weeks or less, and breastfeed more than 8 weeks. Multinomial logistic regression was used to obtain crude and adjusted odds [...] ( n = 67,667) of women reported never breastfeeding. The odds of discontinuing breastfeeding before 8 weeks were 18% higher among women who reported experiencing abuse 12 months before pregnancy compared
