Determination of antiplasmodial activity and binding affinity of selected natural products towards PfTrxR and PfGR (Publications)
naridine, hernagine, vobasine and hispolone displayed antiplasmodial activity against PfK1 (IC50 = 0.996-3.63 microg/mL).
Influences of blood digestion on the development of <em>Plasmodium gallinaceum</em> (Brumpt) in the midgut of <em>Aedes aegypti</em> (L.) (Publications)
are explained by the action of trypsin-like proteases on the parasites and indicate that plasmodia 0-10 h after blood meal are more sensitive to the enzymes than later stages of the parasites
<em>In vivo</em> activity of aryl ozonides against <em>Schistosoma</em> species (Publications)
against adult Schistosoma mansoni, with total and female worm burden reductions of 80 and 90% (P < 0.05), respectively. Furthermore, treatment of S. haematobium-infected mice with OZ418 reduced the total
Laboratory-reflex cryptococcal antigen screening is associated with a survival benefit in Tanzania (Publications)
Our previous 12-month survival/retention in CrAg-positive persons not treated with fluconazole was 0%. METHODS: HIV testing was offered to all ART-naive outpatients and hospitalized patients in Ifakara
Boswellic acids show <em>in vitro</em> activity against <em>Leishmania donovani</em> (Publications)
3-O-acetyl-11-keto-beta-boswellic acid (AKBA) showed the strongest activity with an IC50 value of 0.88 microM against axenic amastigotes but was inactive against intracellular amastigotes in murine m
Haemoglobin changes and risk of anaemia following treatment for uncomplicated falciparum malaria in sub-Saharan Africa (Publications)
analysed using mixed effect models. RESULTS: Eight thousand eight hundred ninety-seven patients (77.0%
Boswellic acids show <em>in vitro</em> activity against <em>Leishmania donovani</em> (Publications)
3-O-acetyl-11-keto-beta-boswellic acid (AKBA) showed the strongest activity with an IC50 value of 0.88 microM against axenic amastigotes but was inactive against intracellular amastigotes in murine m
Haemoglobin changes and risk of anaemia following treatment for uncomplicated falciparum malaria in sub-Saharan Africa (Publications)
analysed using mixed effect models. RESULTS: Eight thousand eight hundred ninety-seven patients (77.0%
<em>Blastocystis</em> in Swiss children: a practical approach (Publications)
There was a high significance in correlation of abdominal pain and chronicity (p < 0.0001) but none in diarrhea (p = 0.082) nor nausea/vomiting or other symptoms and chronicity. Followed by Entamoeba coli
Outpatient treatment of imported uncomplicated <em>Plasmodium falciparum</em> malaria: results from a survey among TropNet and GeoSentinel experts for... (Publications)
semi-immunity. The threshold parasitaemia for outpatient treatment varied from 0.1% to 5% with a median of 2%. A median of 0.5% of outpatients were admitted during follow-up. During the last 10 years, 33