Genetic diversity and protective efficacy of the RTS,S/AS01 malaria vaccine (Publications)
infections), as compared with 33.4% (95% CI, 29.3 to 37.2) against mismatched malaria (1951 infections) (P=0.04 for differential vaccine efficacy). The vaccine efficacy based on the hazard ratio was 62.7% (95% [...] 3) against matched infections versus 54.2% (95% CI, 49.9 to 58.1) against mismatched infections (P=0.06). In the group of infants 6 to 12 weeks of age, there was no evidence of differential allele-specific
Accuracy of urine circulating cathodic antigen (CCA) test for <em>Schistosoma mansoni</em> diagnosis in different settings of Côte d'Ivoire (Publications)
sensitivity of a single CCA-B was 10.4%, 29.9% and 75.0%. The ether-concentration technique showed a low sensitivity for S. mansoni diagnosis (8.3-41.0%). The specificity of CCA-A was moderate (76.9-84.2%);
Intravaginal practices, bacterial vaginosis, and HIV infection in women: individual participant data meta-analysis (Publications)
ects meta-analysis. The level of between-study heterogeneity was low in all analyses (I(2) values 0.0%-16.1%). Intravaginal use of cloth or paper (pooled adjusted hazard ratio [aHR] 1.47, 95% confidence
The usefulness of twenty-four molecular markers in predicting treatment outcome with combination therapy of amodiaquine plus... (Publications)
independent predictors for treatment failure with AQ+SP were pfmdr1 N86Y (OR = 7.87, p < 0.01) and pfdhps A437G (OR = 3.44, p < 0.01). Mutations found in CQ/AQ related markers pfcrt K76T, A220S, N326D, and I356L
Bovine tuberculosis at a cattle-small ruminant-human interface in Meskan, Gurage region, central Ethiopia (Publications)
goat) were reactors. The overall individual prevalence in small ruminants (> 2 mm cut-off) was 0.4% (CI: 0.03-5.1%) with 25% herd prevalence. Cattle from owners with PPD positive small ruminants were all
Self-rated quality of life and school performance in relation to helminth infections: case study from Yunnan, People's Republic of China (Publications)
rates for hookworm, Trichuris trichiura and Ascaris lumbricoides were high in Bulangshan (75.9%, 70.0% and 68.2%), while the respective prevalence rates in Pu'er were 66.9%, 56.5% and 9.2%. Students were [...] between students with varying infection status in the domains of the SF-12 (odds ratio close to 1.0). Somewhat more pronounced, yet not statistically significant differences were observed when end-of
Distribution and risk factors for <em>Plasmodium</em> and helminth co-infections: a cross-sectional survey among children in Bagamoyo district,... (Publications)
prevalence rate of Plasmodium, specific STH and co-infections increased significantly with age (p < 0.001), with older children mostly affected except for S. stercoralis monoinfection and co-infections [...] STH infections to be associated with Plasmodium infection [OR adjusted for age group 1.4, 95% CI (1.0-2.1)], which was more marked for S. stercoralis (OR = 2.2, 95% CI (1.1-4.3). Age and not schooling were
Spatial and socio-demographic determinants of contraceptive use in the upper east region of Ghana (Publications)
year old women who live 2 km or more from a CHPS compound is 0.74 compared to women who live less than 2 km from a CHPS compound (p-value = 0.035). CONCLUSION: The findings suggest that rapid scale up of
Comparability between insecticide resistance bioassays for mosquito vectors: time to review current methodology? (Publications)
% (Cohen's kappa = 0.06). There was better agreement when 24 h mortality was recorded in the CDC bottle assay and compared with that of the WHO susceptibility test (Cohen's kappa = 0.5148). Time-to-knockdown
Respiratory health in cleaners in northern Europe: is susceptibility established in early life? (Publications)
stronger for those with early life disadvantage than in those without (1.8 [1.5-2.3] vs. 1.3 [0.96-1.8]; pinteraction 0.035). CONCLUSIONS: Occupational cleaners had increased risk of asthma and self-reported
