Antibody isotype responses, infection and re-infection for <em>Schistosoma japonicum</em> in a marshland area of China (Publications)
IgA and IgE responses to AWA, PMY and TEG were measured by ELISA. Males produced significantly (P < 0.05) more anti-AWA total IgG, IgE, IgA, IgG4 and IgG2 antibodies, and anti- TEG IgG2 antibody than their [...] not show such an association. Anti-AWA-specific IgE antibody levels were positively correlated (r = 0.55) with anti-AWA specific IgG4 antibody levels. In addition, the overall percentage of responders (using
<em>SERPINA1</em> PiZ and PiS heterozygotes and lung function decline in the SAPALDIA cohort (Publications)
with PiMZ it amounted to 92.2 ml (p?=?0.03). Corresponding numbers for persistent smokers differed even more strongly (66.8 ml (PiMM) vs. 108.2 ml (PiMZ), p?=?0.005). Equivalent, but less strong associations
Comparison of novel and standard diagnostic tools for the detection of<em> Schistosoma mekongi</em> infection in Lao People's Democratic Republic and... (Publications)
and Taenia spp. were 50.4%, 28.1%, 3.5%, 0.3% and 1.9%, respectively. In the urine samples, the tests for CCA and CAA detected S. mekongi infections in 21.0% and 38.7% of the study participants, respectively
Status of soil-transmitted helminth infections in schoolchildren in Laguna Province, the Philippines: determined by parasitological and molecular... (Publications)
was 40.6%, 30.3%, and 44.0%, respectively. The qPCR method also detected infections with Ancylostoma spp. (4.6%), Necator americanus (2.3%), and Strongyloides stercoralis (0.8%) that were missed by KK
Mosquito net coverage in years between mass distributions: a case study of Tanzania, 2013 (Publications)
population was low (LLINs: 32.8%; UTNs: 9.5%) and net use:access ratio was below target level (LLINs: 0.66; UTN: 0.50). Both measures varied significantly by district. CONCLUSIONS: Two years after the last mass
Transfer of enteric viruses (adenovirus and coxsackievirus) and bacteriophage (MS2) from liquid to human skin (Publications)
MS2 adsorbed on the skin was significantly higher than both adenovirus (average 0.74 log10) and coxsackievirus (average 0.61 log10). Quantification of pathogenic virus retention to skin would thus be o
Efficacy of artemether-lumefantrine and dihydroartemisinin-piperaquine for the treatment of uncomplicated malaria in Papua New Guinea (Publications)
(104/106) for AL and 100% (135/135) for DHA-PPQ. The day-42 PCR-corrected ACPR for P. vivax was 79.0% (15/19) for AL and 92.3% (36/39) for DHA-PPQ. Day 3 parasite clearance of P. falciparum was 99.2% with [...] revealed low susceptibility to chloroquine (34% of samples above IC50 threshold) but not to lumefantrine (0%). Molecular markers assessed in a sub-set of the study population indicated high rates of chloroquine
Rapid multiplex gene expression assays for monitoring metabolic resistance in the major malaria vector <em>Anopheles gambiae</em> (Publications)
novel assays are efficient (reaction efficiencies = 95-109%), sensitive (covering a > 10.0 Ct range with R(2) values > 0.99), specific (TaqMan chemistry), reproducible (%CV = 4.46-12.07%), as well as readily
Spatiotemporal modelling of airborne birch and grass pollen concentration across Switzerland: a comparison of statistical, machine learning and... (Publications)
hybrid model. RESULTS: The 5(th)-95(th) percentiles of birch and grass pollen concentrations were 0-151 and 0-105 grains/m(3), respectively. The hybrid ensemble model achieved the best RMSE on the test dataset
Seasonal malaria chemoprevention and the spread of <em>Plasmodium falciparum </em>quintuple-mutant parasites resistant to sulfadoxine-pyrimethamine: a... (Publications)
95% initial coverage declining each cycle), the quintuple mutant required 53·1 years (95% CI 50·5-56·0) to spread from 1% to 50% of inoculations. This time increased in lower-transmission settings and reduced [...] deployed. For the same setting, the effective reduction in clinical cases in children receiving SMC was 79·0% (95% CI 77·8-80·8) and 60·4% (58·6-62·3) during the months of SMC implementation when the quintuple