First clinical trial of purified, irradiated malaria sporozoites in humans (Publications)
JE, Tewari K, Lyke KE et al. Live attenuated malaria vaccine designed to protect through hepatic CD8 T cell immunity. Science 334(6055), 475-480 (2011). Purified, irradiated, metabolically active sporozoites [...] challenge with infected mosquitoes. Intravenous delivery of PfSPZ in nonhuman primates induced memory CD8(+) and CD4(+) T cells specific for PfSPZ that reside in the liver. Further studies using PfSPZ and the
Prévalence des diarrhées infantojuvéniles dans deux districts de Nouakchott (Mauritanie) en 2008: analyse de l'influence de l'hygiène du milieu... (Publications)
diarrhea, for an average prevalence of 14.8% that varied by age (23.6% in children younger than 5 years and 9.7% among children aged 5 to 14 years) and area (16.8% in Tevragh-Zeina and 28.3% in Sebkha).
Erfahrungen mit dem Tuberkulin TIne-Test bei Reihenuntersuchungen (Publications)
Berna according to Mantoux. 357 (14.8%) showed positive reactions. Since not all tine-negative pupils were submitted to a Mantoux test, it must be assumed that 14.8% false negatives were missed in the
First clinical trial of purified, irradiated malaria sporozoites in humans (Publications)
JE, Tewari K, Lyke KE et al. Live attenuated malaria vaccine designed to protect through hepatic CD8 T cell immunity. Science 334(6055), 475-480 (2011). Purified, irradiated, metabolically active sporozoites [...] challenge with infected mosquitoes. Intravenous delivery of PfSPZ in nonhuman primates induced memory CD8(+) and CD4(+) T cells specific for PfSPZ that reside in the liver. Further studies using PfSPZ and the
Prévalence des diarrhées infantojuvéniles dans deux districts de Nouakchott (Mauritanie) en 2008: analyse de l'influence de l'hygiène du milieu... (Publications)
diarrhea, for an average prevalence of 14.8% that varied by age (23.6% in children younger than 5 years and 9.7% among children aged 5 to 14 years) and area (16.8% in Tevragh-Zeina and 28.3% in Sebkha).
Clinical outcome of febrile Tanzanian children with severe malnutrition using anthropometry in comparison to clinical signs (Publications)
7 (per-protocol), was 1.8% (1/56) in the ePOCT arm versus 16.7% (8/48) in the Algorithm for the MANagement of Childhood illnesses arm (risk difference -14.9%, 95% CI -26.0%, -3.8%; risk ratio 0.11, 95%
Systematic review and meta-analysis of tuberculosis in animals in Nigeria (Publications)
analyses showed an overall pooled TB prevalence of 7.0% (95% CI: 6.0–8.0) comprising of infection distributed in cattle (8.0%, 95% CI: 7.0–8.0), goats (0.47%, 95% CI: 0–1.2), sheep (0.27%, 95% CI: 0.14–0.46)
Effects of age, gender and soil-transmitted helminth infection on prevalence of <em>Plasmodium </em>infection among population living in Bata... (Publications)
infections were detected in 34.8% of the participants, while 50% of malaria infections were reported in children aged 10-17 years. Females had a lower prevalence of malaria (28.8%) compared with males (41.7%) [...] trichiura had malaria parasites compared with those infected with A. lumbricoides (39.6%) or both (46.8%). CONCLUSIONS: The overlapping problem of STH and malaria is neglected in Bata. The current study forces
Accuracy of two circulating antigen tests for the diagnosis and surveillance of <em>Schistosoma mansoni </em>infection in low-endemicity settings of... (Publications)
POC-CCA (37.6%) and six Kato-Katz thick smears (13.8%). The negative predictive value of UCP-LF CAA, POC-CCA, and six Kato-Katz thick smears was 92.8%, 79.8%, and 74.1%, respectively. Our results confirm that
Challenges in routine implementation and quality control of rapid diagnostic tests for malaria: Rufiji District, Tanzania (Publications)
reference microscopy was 64.8%, but varied greatly by health facility, range 18.8-85.9%. Sensitivity of RDTs increased with increasing parasite density. Specificity remained high at 87.8% despite relatively poor
