Potential contribution of HIV during first-line tuberculosis treatment to subsequent rifampicin-monoresistant tuberculosis and acquired tuberculosis... (Publications)
WGS data showing MDR or rifampicin-resistant tuberculosis were available for 1169 patients; 360 (30.8%) isolates were identified as unique. In previously treated patients, RMR tuberculosis versus MDR t
Cancer risk in adolescents and young adults living with HIV in South Africa: a nationwide cohort study (Publications)
Kaposi sarcoma (2.06, 1.61-2.63), non-Hodgkin lymphoma (3.17, 2.06-4.89), Hodgkin lymphoma (4.83, 2.61-8.93), and leukaemia (unadjusted HR 5.90, 95% CI 2.87-12.12). Cancer rates decreased over the study period
Long-term exposure to low-level ambient air pollution and incidence of stroke and coronary heart disease: a pooled analysis of six European cohorts... (Publications)
participants were analysed in our fully adjusted model. During a median follow-up of 17.2 years (IQR 13.8-19.5), we observed 6950 incident events of stroke and 10 071 incident events of coronary heart disease
Global, regional, and national burden of mortality associated with non-optimal ambient temperatures from 2000 to 2019: a three-stage modelling study (Publications)
associated with non-optimal temperatures per year, accounting for 9.43% (95% eCI 7.58-11.07) of all deaths (8.52% [6.19-10.47] were cold-related and 0.91% [0.56-1.36] were heat-related). There were 74 temperat
The consequences of declining population access to insecticide-treated nets (ITNs) on net use patterns and physical degradation of nets after 22... (Publications)
slept under ITNs. In households without sufficient nets, pregnant women (54.6%), children < 5 years (45.8%) and adults (42.1%) were prioritized, with fewer school-age children 5-14 years (35.9%), youths 15-24
Short-term effects of nocturnal transportation noise on cardio-metabolic outcomes and its association to sleep (Publications)
age and sex modulate the observed noise effects? Twenty-six (12 women) young (19-33 years) and 16 (8 women) older (52-70 years) volunteers participated in a six day controlled laboratory study. The experiment
Increasing rabies data availability: the example of a One Health research project in Chad, Côte d'Ivoire and Mali (Publications)
collected on bite incidents and health seeking from over 24'000 households, on access to treatment of over 8'800 bite cases registered in public health facilities and on the status of over 1'800 rabies suspect
Clinical trial evidence supporting US Food and Drug Administration approval of novel cancer therapies between 2000 and 2016 (Publications)
106-448 participants). Overall, 65 clinical trials (51.2%) were randomized, and 95 clinical trials (74.8%) were open label. Of 100 indications, 44 indications underwent accelerated approval, 42 indications
Safety and efficacy of the RTS,S/AS01(E) candidate malaria vaccine given with expanded-programme-on-immunisation vaccines: 19 month follow-up of a... (Publications)
developed for immunisation of infants in Africa through the expanded programme on immunisation (EPI). 8 month follow-up data have been reported for safety and immunogenicity of RTS,S/AS01(E) when integrated
Evaluation of the pharmacokinetic profile of artesunate, artemether and their metabolites in sheep naturally infected with <em>Fasciola hepatica</em> (Publications)
n) and AUCs (area under the plasma concentration-time curve) were observed for artesunate (C(max): 8.4x10(3) and 9.4x10(3)ng/ml; AUC: 6.9x10(5) and 9.7x10(5)ngmin/ml), DHA (C(max): both 2.4x10(3)ng/ml;
