The prevalence and risk of urinary tract infection in malnourished children: a systematic review and meta-analysis (Publications)
3294 malnourished children was 17% (95% CI, 13, 21%). Heterogeneity was high (I(2) = 87.6%; Tau(2) = 0.06) as studies varied in their sample size, degree of malnutrition, and study period. Multivariate [...] controls) was 2.34 (95% CI, 1.15, 3.34), with lower between-study heterogeneity (I(2) = 53.6%; Tau(2) = 0.47). CONCLUSIONS: UTI is more prevalent in malnourished children than in their well-nourished counterparts
Multi-center screening of the Pathogen Box collection for schistosomiasis drug discovery (Publications)
were compared at 72 h, concordance remained a robust 74%. Further, robust Pearson's correlations (0.48-0.68) were measured between the assays. Of those actives at 72 h, the UCSD, Swiss TPH and FIOCRUZ assays
Challenges in diagnosing scrub typhus among hospitalized patients with undifferentiated fever at a national tertiary hospital in northern Vietnam (Publications)
), and having a comorbidity and neutrophilia were significantly less common in ST cases (aORs: 0.29 and 0.27, respectively). The majority of the ST cases were not clinically diagnosed with rickettsiosis
Long-term air pollution exposure is associated with increased severity of rhinitis in 2 European cohorts (Publications)
Pollution Effects project, at the participants' residential address. The score of rhinitis severity (range, 0-12), based on intensity of disturbance due to symptoms reported by questionnaire, was categorized into [...] rhinitis severity (adjusted odds ratio [95% CI] for a 10 mug/m(3) increase in PM10: for mild: 1.20 [0.88-1.64], moderate: 1.53 [1.07-2.19], and high severity: 1.72 [1.23-2.41]). Similar results were found
Tetrahydropyridinylidene ammonium salts with arylalkyl and diarylalkyl substitution and their antiprotozoal activity (Publications)
The most active compounds showed activity against Trypanosoma brucei rhodesiense in concentrations < 0.06 mu M. A series of compounds was active against Plasmodium falciparum NF54 in low nanomolar concentration
Exposure to radio-frequency electromagnetic fields from broadcast transmitters and risk of childhood cancer: a census-based cohort study (Publications)
cancer cases, adjusted hazard ratios in the time-to-event analysis for the highest exposure category (> 0.2 V/m) as compared with the reference category (
<em>In vitro</em> and in vivo evaluation of the antitrypanosomal activity of fractions of Holarrhena africana (Publications)
as HaF(5) showed in vitro activity against Trypanosoma brucei rhodesiense with an IC(50) value of 0.785 microg/mg and no overt cytotoxicity against L-6 cells. Fraction HaF(5) was tested in vivo at two
Epidemiology of <em>Opisthorchis viverrini</em> in a rural district of southern Lao PDR (Publications)
(median age 16 years, 51.5% women). The prevalence was 58.5%. Infection rates increased with age (from 20.0 to 85.5%; P
Novel 4-[4-(4-methylpiperazin-1-yl)phenyl]-6-arylpyrimidine derivatives and their antitrypanosomal activities against <em>T.brucei</em> (Publications)
s with promising antitrypanosomal activity. In particular, 32 exhibits an in vitro EC(50) value of 0.5 µM against Trypanosoma brucei rhodesiense, and analogues 29, 30 and 33 show antitrypanosomal activities
Novel 4-[4-(4-methylpiperazin-1-yl)phenyl]-6-arylpyrimidine derivatives and their antitrypanosomal activities against <em>T.brucei</em> (Publications)
s with promising antitrypanosomal activity. In particular, 32 exhibits an in vitro EC(50) value of 0.5 µM against Trypanosoma brucei rhodesiense, and analogues 29, 30 and 33 show antitrypanosomal activities
