Tetrahydropyridinylidene ammonium salts with arylalkyl and diarylalkyl substitution and their antiprotozoal activity (Publications)
The most active compounds showed activity against Trypanosoma brucei rhodesiense in concentrations < 0.06 mu M. A series of compounds was active against Plasmodium falciparum NF54 in low nanomolar concentration
Exposure to radio-frequency electromagnetic fields from broadcast transmitters and risk of childhood cancer: a census-based cohort study (Publications)
cancer cases, adjusted hazard ratios in the time-to-event analysis for the highest exposure category (> 0.2 V/m) as compared with the reference category (
<em>In vitro</em> and in vivo evaluation of the antitrypanosomal activity of fractions of Holarrhena africana (Publications)
as HaF(5) showed in vitro activity against Trypanosoma brucei rhodesiense with an IC(50) value of 0.785 microg/mg and no overt cytotoxicity against L-6 cells. Fraction HaF(5) was tested in vivo at two
Epidemiology of <em>Opisthorchis viverrini</em> in a rural district of southern Lao PDR (Publications)
(median age 16 years, 51.5% women). The prevalence was 58.5%. Infection rates increased with age (from 20.0 to 85.5%; P
per 100,000 inhabitants died of tuberculosis in Switzerland each year. Today, the figure is around 0.2 per 100,000 inhabitants per year. In Lesotho, on the other hand, the figure is a thousand times higher:
Latent tuberculosis infection prevalence in rural Madagascar (Publications)
district, Madagascar. RESULTS: Of adults, 78.6% were positive for LTBI, ranging between 28.6% and 95.0% among villages. The majority (65.3%) showed an induration reaction of > 15 mm. CONCLUSIONS: LTBI prevalence
Synthesis of a small library of 2-phenoxy-1,4-naphthoquinone and 2-phenoxy-1,4-anthraquinone derivatives bearing anti-trypanosomal and... (Publications)
Trypanosoma brucei rhodesiense, Leishmania donovani, and Trypanosoma cruzi cells (IC(50)=50nM, IC(50)=0.28microM, and IC(50)=1.26microM, respectively)
Klinische Bewertung von Ciclobendazol (C-C 2481) bei der Behandlung von Wurmerkrankungen des Darmes (Publications)
small number of cases of ankylostomiasis, the values were, however, considerable lower (38.5 and 20.0% respectively). Since ciclobendazole is well tolerated, there is a need for studies with higher dosages
Spirotetrahydro beta-carbolines (spiroindolones): a new class of potent and orally efficacious compounds for the treatment of malaria (Publications)
IC(50) of 90 nM. Structure-activity relationships for the optimization of 1 to compound 20a (IC(50) = 0.2 nM) including the identification of the active 1R,3S enantiomer and elimination of metabolic liabilities
High prevalence of <em>Strongyloides stercoralis</em> among school children in rural Côte d'Ivoire (Publications)
method, or both techniques. The prevalence of S. stercoralis at the unit of the school ranged between 4.0 and 48%. Because S. stercoralis is a neglected nematode, yet an important parasite from a public health
