BMI group-related differences in physical fitness and physical activity in preschool-age children: a cross-sectional analysis (Publications)
(balance platform), and physical activity (PA, accelerometers) in 613 children (M age = 5.1 years, SD = 0.6). Normal weight (NW) children performed better than overweight (OW) children in aerobic fitness, agility
Fluorinated rhodacyanine (SJL-01) possessing high efficacy for visceral leishmaniasis (VL) (Publications)
e derivatives have been examined. Among them, the fluorinatied variant SJL-01 (8) showed IC(50) of 0.011 microM against Leishmania donovani strain MHOM/ET/67/L82 (selective index of > 15000) and 95-97%
An evaluation of minor groove binders as anti-fungal and anti-mycobacterial therapeutics (Publications)
detailed investigation and optimisation. MGB-4, MGB-317 and MGB-325 have promising MIC80s of 2, 4 and 0.25 mug/mL, respectively, against the fungus C. neoformans.MGB-353 and MGB-354 have MIC99s of 3.1 muM
Heterogeneities in the transmission of infectious agents: implications for the design of control programs (Publications)
contributes at least 80% of the net transmission potential, as measured by the basic reproduction number, R0. This is an example of a statistical pattern known as the 20/80 rule. The rule applies to a variety
Heterogeneities in the transmission of infectious agents: implications for the design of control programs (Publications)
contributes at least 80% of the net transmission potential, as measured by the basic reproduction number, R0. This is an example of a statistical pattern known as the 20/80 rule. The rule applies to a variety
Latent tuberculosis infection prevalence in rural Madagascar (Publications)
district, Madagascar. RESULTS: Of adults, 78.6% were positive for LTBI, ranging between 28.6% and 95.0% among villages. The majority (65.3%) showed an induration reaction of > 15 mm. CONCLUSIONS: LTBI prevalence
Synthesis of a small library of 2-phenoxy-1,4-naphthoquinone and 2-phenoxy-1,4-anthraquinone derivatives bearing anti-trypanosomal and... (Publications)
Trypanosoma brucei rhodesiense, Leishmania donovani, and Trypanosoma cruzi cells (IC(50)=50nM, IC(50)=0.28microM, and IC(50)=1.26microM, respectively)
Klinische Bewertung von Ciclobendazol (C-C 2481) bei der Behandlung von Wurmerkrankungen des Darmes (Publications)
small number of cases of ankylostomiasis, the values were, however, considerable lower (38.5 and 20.0% respectively). Since ciclobendazole is well tolerated, there is a need for studies with higher dosages
Spirotetrahydro beta-carbolines (spiroindolones): a new class of potent and orally efficacious compounds for the treatment of malaria (Publications)
IC(50) of 90 nM. Structure-activity relationships for the optimization of 1 to compound 20a (IC(50) = 0.2 nM) including the identification of the active 1R,3S enantiomer and elimination of metabolic liabilities
High prevalence of <em>Strongyloides stercoralis</em> among school children in rural Côte d'Ivoire (Publications)
method, or both techniques. The prevalence of S. stercoralis at the unit of the school ranged between 4.0 and 48%. Because S. stercoralis is a neglected nematode, yet an important parasite from a public health
