An in-depth report of quality control on Kato-Katz and data entry in four clinical trials evaluating the efficacy of albendazole against... (Publications)
BACKGROUND: Efforts to control soil-transmitted helminth (STH) infections have intensified over the past decade. Field-survey data on STH prevalence, infection intensity and drug efficacy is necessary [...] (FECs) and data entry, and compared the prevalence of any STH infection and moderate-to-heavy intensity (MHI) infections and the drug efficacy against STH infections. RESULTS: Across the four study sites, a [...] varied from ~3% (hookworms) to ~6.5% (Ascaris lumbricoides and Trichuris...
between WASH and STH as well as planned actions of the health sector or other actors for STH survey, control and prevention; To collect available epidemiological information regarding STH endemicity in the [...] partners/laboratories qualified to carry out such work, and provide recommendations for intensified STH control and prevention. To assess the current capacity of the country to improve the WASH conditions
Water, sanitation, hygiene, and soil-transmitted helminth infection: a systematic review and meta-analysis (Publications)
soil-transmitted helminth (STH) infection. METHODS AND FINDINGS: We conducted a systematic review and meta-analysis to examine the associations of improved WASH on infection with STH (Ascaris lumbricoides, [...] 57, 95% CI 0.45-0.72), but not any STH infection (OR 0.93, 95% CI 0.28-3.11). Access to sanitation was associated with decreased likelihood of infection with any STH (OR 0.66, 95% CI 0.57-0.76), T. trichiura [...] eligible for inclusion if they provided an estimate for the effect of WASH...
Water, sanitation, hygiene, and soil-transmitted helminth infection: a systematic review and meta-analysis (Publications)
soil-transmitted helminth (STH) infection. METHODS AND FINDINGS: We conducted a systematic review and meta-analysis to examine the associations of improved WASH on infection with STH (Ascaris lumbricoides, [...] 57, 95% CI 0.45-0.72), but not any STH infection (OR 0.93, 95% CI 0.28-3.11). Access to sanitation was associated with decreased likelihood of infection with any STH (OR 0.66, 95% CI 0.57-0.76), T. trichiura [...] eligible for inclusion if they provided an estimate for the effect of WASH...
Assessment of fecal calprotectin and fecal occult blood as point-of-care markers for soil-transmitted helminth attributable intestinal morbidity in a... (Publications)
relationship between intestinal morbidity and STH infections. Suitable, standardized, low-cost markers of STH attributable morbidity to better monitor the impact of STH control interventions are necessary. Funding: [...] for Trichuris trichiura and concomitant STH infections from three countries was used to perform FC and FOB point-of-care assays. Simultaneously, identified STH negative participants underwent FC and FOB [...] regression. Findings: In total, 1034 T. trichiura infected cases...
Assessment of fecal calprotectin and fecal occult blood as point-of-care markers for soil-transmitted helminth attributable intestinal morbidity in a... (Publications)
relationship between intestinal morbidity and STH infections. Suitable, standardized, low-cost markers of STH attributable morbidity to better monitor the impact of STH control interventions are necessary. Funding: [...] for Trichuris trichiura and concomitant STH infections from three countries was used to perform FC and FOB point-of-care assays. Simultaneously, identified STH negative participants underwent FC and FOB [...] regression. Findings: In total, 1034 T. trichiura infected cases...
Schistosomiasis and soil-transmitted helminthiasis: common drugs for treatment and control (Publications)
for sub-Saharan Africa are that it kills > 200000 people every year. Soil-transmitted helminthiasis (STH) is caused by intestinal nematodes. More than 2 billion people are infected worldwide and the disease [...] approach that of malaria. Recognising the enormous public health significance of schistosomiasis and STH, particularly among the poor, and in view of readily available drugs that are safe, efficacious and [...] briefly summarises the geographical distribution, life cycle and global...
Schistosomiasis and soil-transmitted helminthiasis: common drugs for treatment and control (Publications)
for sub-Saharan Africa are that it kills > 200000 people every year. Soil-transmitted helminthiasis (STH) is caused by intestinal nematodes. More than 2 billion people are infected worldwide and the disease [...] approach that of malaria. Recognising the enormous public health significance of schistosomiasis and STH, particularly among the poor, and in view of readily available drugs that are safe, efficacious and [...] briefly summarises the geographical distribution, life cycle and global...
that globally monitors the eficacy of drugs and spread of AR in STH programs, and hence prevailing the success of MDA programs to eliminate STH as a public problem by 2020. The specific objectives are (i) [...] establishment of a surveillance system to monitor the global patterns of effectiveness of drugs and AR in STH programs (iii) the development of supporting tools for planning, analysis and following-up of the
Distribution and risk factors for <em>Plasmodium</em> and helminth co-infections: a cross-sectional survey among children in Bagamoyo district,... (Publications)
(1.1-4.3). Age and not schooling were risk factors for Plasmodium and STH co-infection. CONCLUSION: The findings suggest that STH and Plasmodium infections tend to occur in the same children, with increasing [...] BACKGROUND: Plasmodium and soil transmitted helminth infections (STH) are a major public health problem, particularly among children. There are conflicting findings on potential association between these [...] blood samples were examined using a broad set of quality controlled...