The <em>in vitro</em> distribution of halofantrine in human blood and <em>Plasmodium falciparum</em>-parasitised red blood cells (Publications)
total drug. It was not significantly bound to thrombocytes (2%), lymphocytes (1%) or granulocytes (0.3%). The distribution of halofantrine into Plasmodium falciparum-parasitised red blood cells was measured
Trypanocidal, leishmanicidal and cytotoxic effects of anthecotulide-type linear sesquiterpene lactones from Anthemis auriculata (Publications)
to be the most active compound against all parasites, particularly towards T. b. rhodesiense (IC(50) 0.56 microg/ml), whereas 4-acetoxyanthecotulide (3) was the least active. All three metabolites possessed
Impact of body temperature on in-hospital and long-term mortality in patients with acute heart failure (Publications)
Morbidity was documented as secondary endpoint. RESULTS: BT on presentation was 37.2 degrees C (SD 0.9) and ranged from 34.8-40.4 degrees C. Patients were divided into quartiles of BT. Initial morbidity
Single pollutant versus surrogate measure approaches: do single pollutant risk assessments underestimate the impact of air pollution on lung cancer... (Publications)
years. This estimate was considerably higher than the unit risk-based estimate yielding 1.1 (range, 0.45-2.8) cancer cases per 100,000 person years. We discuss these discrepancies in light of inherent
Preparedness of anesthesiologists working in humanitarian disasters (Publications)
should improve preparedness for anesthesia personnel. (Disaster Med Public Health Preparedness. 2013;0;1-5).
Mathematical models of contact patterns between age groups for predicting the spread of infectious diseases (Publications)
analysis to the spread of a smallpox-like disease, derive the formula for the reproduction number, R0, and based on this threshold parameter, show the level of human behavioral change required to control
Structure elucidation and antimalarial activity of apicidin F: an apicidin-like compound produced by <em>Fusarium fujikuroi</em> (Publications)
Activity evaluation against Plasmodium falciparum showed good in vitro activity with an IC50 value of 0.67 muM
Survey on animal bite injuries and their management to estimate human rabies deaths in N'Djamena, Chad (Publications)
estimated annual incidence of bites from suspected rabid animals of 12.9/100 000 and an incidence of 0.7 human rabies deaths/100 000, resulting in 7 estimated deaths (95% confidence interval 4-10 deaths)
Prevalence and risk factors for carriage of multi-drug resistant <em>Staphylococci</em> in healthy cats and dogs (Publications)
risk of colonisation by multi-drug resistant Staphylococci (OR = 2.4, 95% CI: 1.1 5.2, p value LRT = 0.04). When identifying efficient control strategies against antibiotic resistance, the presence of mechanisms
Effect of supervised training on FEV1 in cystic fibrosis: a randomised controlled trial (Publications)
6months. RESULTS: FEV1 increased significantly in both training groups compared with CONCH (AT:+5.8±0.95, ST:+7.4±2.5, CONCH:-11.5±2.7% predicted, p
