Similar prevalence of <em>Plasmodium falciparum</em> and Non-<em>P. falciparum</em> malaria infections among schoolchildren, Tanzania (Publications)
Among 3,456 schoolchildren, 22% had P. falciparum, 24% had P. ovale spp., 4% had P. malariae, and 0.3% had P. vivax infections. Most (91%) schoolchildren with P. ovale infections had low parasite densities;
Expanding the activity profile of pyrido[1,2-a]benzimidazoles: synthesis and evaluation of novel n(1)-1-phenylethanamine derivatives against... (Publications)
Here, we report a novel series of antischistosomal PBIs with potent in vitro activity (IC50 values of 0.08-1.43 muM) against Schistosoma mansoni newly transformed schistosomula and adult worms. Moreover,
Synthesis, <em>in vitro</em> antiprotozoal activity, molecular docking and molecular dynamics studies of some new monocationic guanidinobenzimidazoles (Publications)
throughout 200 ns time. Root mean square deviation (RMSD) values of the ligands remained stable below 0.25 mm and root mean square fluctuation (RMSF) values of the active site residues with which it interacted
The "double burden of malnutrition" in the Amazon: dietary change and drastic increases in obesity and anemia over 40 years among the Awajun (Publications)
obesity were also substantially higher in 2013 compared to the 1970s (23% vs 6% for anemia and 30% vs. 0% for obesity) indicating a DBM has emerged. Examining the predictors of hemoglobin levels and body mass
The discovery of novel antitrypanosomal 4-phenyl-6-(pyridin-3-yl)pyrimidines (Publications)
compound 13, the 4-(2-methoxyphenyl)-6-(pyridine-3-yl)pyrimidin-2-amine demonstrating an IC50 value of 0.38 muM and a promising off-target ADME-Tox profile in vitro. In silico molecular target investigations
Complement factor D, albumin, and immunoglobulin G anti-band 3 protein antibodies mimic serum in promoting rosetting of malaria-infected red blood... (Publications)
Complement factor D alone induced 30 to 40% of de novo rosetting. Its effect was additive to that of 0.5 mg/ml albumin and to that of 15 ng/ml of naturally occurring antibodies to the anion transport protein
Changing patterns of soil-transmitted helminthiases in Zanzibar in the context of national helminth control programs (Publications)
1994, the prevalence of S. stercoralis, hookworm, A. lumbricoides, and T. trichiura decreased by 81.0%, 80.5%, 70.6%, and 48.6%, respectively. Infection intensities decreased by > 95% for all helminth species
Diagnosis, clinical features, and self-reported morbidity of <em>Strongyloides stercoralis</em> and hookworm infection in a co-endemic setting (Publications)
helminth infection status. PRINCIPAL FINDINGS: The prevalence of hookworm and S. stercoralis was 51.0% and 12.7%, respectively. Both infections were strongly associated with each other (adjusted odds ratio
Independent contribution of parental migrant status and educational level to adiposity and eating habits in preschool children (Publications)
contribution in preschoolers. SUBJECTS/METHODS: Of 655 randomly selected preschoolers, 542 (5.1+/-0.6 years; 71% of parental MS and 37% of low parental EL) were analysed. Body composition was measured
Ultraviolet emission spectra of sunbeds (Publications)
values 10 to 15 times higher in the UVA (320-400 nm) range. An average erythema-effective irradiance of 0.33 W/m2 was determined for sunbeds. This corresponds to a UV index of 13, which is significantly higher
