Synthesis and activity of azaterphenyl diamidines against <em>Trypanosoma brucei rhodesiense</em> and <em>Plasmodium falciparum</em> (Publications)
of those exhibited IC(50) values less than 6 nM against P. f. and six of those showed IC(50) values 0.6 nM, which are more than 25-fold as potent as furamidine. Moreover, two of them showed more than 40-fold
Imported falciparum malaria in Europe: sentinel surveillance data from the European network on surveillance of imported infectious diseases (Publications)
, all deaths occurred in this group. Compared with European standards, the mortality rate was low (0.6% in Europeans). Data from TropNetEurop member sites can contribute to our understanding of the ep
Anthelminthic properties of mangostin and mangostin diacetate (Publications)
Single oral doses (400mg/kg and 800mg/kg) of the drugs achieved worm burden reductions ranging from 0 to 38% and 11-54% against S. mansoni and E. caproni in vivo, respectively. Pharmacokinetic studies would
Synthesis and in vitro antimalarial testing of neocryptolepines: SAR study for improved activity by introduction and modifications of side chains at... (Publications)
And 17i showed an IC50 of 2.2 nM for CQR (K1), a selectivity index of 1243 and a resistance index of 0.5
Emergence chez l’homme de fasciolose à <em>Fasciola gigantica</em> et de distomatose intestinale à <em>Fasciolopsis buski</em> au Laos (Publications)
in slaughterhouses ranged from 17 to 57%, with higher percentages in buffalo (75-100%) than in cows (0-25%). In Laotian villages, the prevalence of human fascioliasis reached 2.4 % after a stool examination
High collection efficiency electrostatic precipitator for in vitro cell exposure to concentrated ambient particulate matter (PM) (Publications)
efficiency under optimized conditions is higher than 95% across all particle diameters measured (18 nm to 3.0 mu m), regardless of aerosol type. The field experiments showed that the VACES with a tandem-virtual
Source apportionment of ambient PM2.5 at five spanish centres of the european community respiratory health survey (ECRHS II) (Publications)
data, showing that traffic was the main source of PM2.5 at the five sites (39-53% of PM2.5, 5.1-12.0 mgm
Gastrointestinal parasite egg excretion in young calves in periurban livestock production in Mali (Publications)
conducted to report the current control strategies. We found eggs of Strongyloides papillosus (Age class 0-1 month: prevalence 39%, 2-3 months: 59%, 5-6 months: 42%), strongyles (14%, 24%, 36%), coccidian oocysts
1-Aryl-1,2,3,4-tetrahydroisoquinolines as potential antimalarials: synthesis, in vitro antiplasmodial activity and in silico pharmacokinetics... (Publications)
displayed moderate antiplasmodial activity and two compounds were found to be highly active (IC50 < 0.2 mu g ml(-1)). The two highly active compounds, 1-(4-chlorophenyl)-6-hydroxyl-1,2,3,4tetrahydroisoquinoline
<em>Opisthorchis viverrini</em>: efficacy and tegumental alterations following administration of tribendimidine in vivo and in vitro (Publications)
tribendimidine administered to O. viverrini-infected hamsters yielded a worm burden reduction of 63.0%. In conclusion, our experiments confirm that tribendimidine possesses interesting trematocidal properties