Gastrointestinal parasite egg excretion in young calves in periurban livestock production in Mali (Publications)
conducted to report the current control strategies. We found eggs of Strongyloides papillosus (Age class 0-1 month: prevalence 39%, 2-3 months: 59%, 5-6 months: 42%), strongyles (14%, 24%, 36%), coccidian oocysts
1-Aryl-1,2,3,4-tetrahydroisoquinolines as potential antimalarials: synthesis, in vitro antiplasmodial activity and in silico pharmacokinetics... (Publications)
displayed moderate antiplasmodial activity and two compounds were found to be highly active (IC50 < 0.2 mu g ml(-1)). The two highly active compounds, 1-(4-chlorophenyl)-6-hydroxyl-1,2,3,4tetrahydroisoquinoline
<em>Opisthorchis viverrini</em>: efficacy and tegumental alterations following administration of tribendimidine in vivo and in vitro (Publications)
tribendimidine administered to O. viverrini-infected hamsters yielded a worm burden reduction of 63.0%. In conclusion, our experiments confirm that tribendimidine possesses interesting trematocidal properties
Validation of a point-of-care circulating cathodic antigen urine cassette test for <em>Schistosoma mansoni</em> diagnosis in the Sahel, and potential... (Publications)
POC-CCA urine cassette tests revealed a Schistosoma mansoni prevalence of 6.9%, compared with only 0.5% by stool microscopy. Four pregnant women with negative coprology had positive POC-CCA. This observation
The locus <em>C11orf30</em> increases susceptibility to poly-sensitization (Publications)
C11orf30-rs2155219, doubles the risk of poly-sensitization (specific IgE/4 allergens: OR = 1.81, 95% CI 0.80-4.24; skin prick test/4+ allergens: OR = 2.27, 95% CI 1.34-3.95). The association of rs2155219 with
Repurposing a library of human cathepsin L ligands: identification of macrocyclic lactams as potent rhodesain and <em>trypanosoma brucei... (Publications)
rats determined. When tested in vivo in acute HAT model, the compounds permitted up to 16.25 (vs 13.0 for untreated controls) mean days of survival.
Measuring universal health coverage based on an index of effective coverage of health services in 204 countries and territories, 1990-2019: a... (Publications)
approximate access to quality care; outcome-based measures were transformed to values on a scale of 0-100 based on the 2.5th and 97.5th percentile of location-year values. We constructed the UHC effective [...] In 2019, the UHC effective coverage index was associated with pooled health spending per capita (r=0.79), although countries across the development spectrum had much lower UHC effective coverage than is [...] people benefiting from UHC during this time. Current projections point to an...
The effects and contribution of childhood diseases on the geographical distribution of all-cause under-five mortality in Uganda (Publications)
national level, 97% (PAF=96.9; 95%BCI: 94.4, 98.0), 91% (PAF=90.9; 95%BCI: 84.4, 95.3), 89% (PAF=89.3; 95%BCI: 76.0,93.8) and 93% (PAF=93.3 95%BCI: 87.7,96.0) of the deaths among children less than five years
Measuring universal health coverage based on an index of effective coverage of health services in 204 countries and territories, 1990-2019: a... (Publications)
approximate access to quality care; outcome-based measures were transformed to values on a scale of 0-100 based on the 2.5th and 97.5th percentile of location-year values. We constructed the UHC effective [...] In 2019, the UHC effective coverage index was associated with pooled health spending per capita (r=0.79), although countries across the development spectrum had much lower UHC effective coverage than is [...] people benefiting from UHC during this time. Current projections point to an...
The effects and contribution of childhood diseases on the geographical distribution of all-cause under-five mortality in Uganda (Publications)
national level, 97% (PAF=96.9; 95%BCI: 94.4, 98.0), 91% (PAF=90.9; 95%BCI: 84.4, 95.3), 89% (PAF=89.3; 95%BCI: 76.0,93.8) and 93% (PAF=93.3 95%BCI: 87.7,96.0) of the deaths among children less than five years