Synthesis and antiprotozoal activity of cationic 1,4-diphenyl-1<em>H</em>-1,2,3-triazoles (Publications)
more active than artemisinin (IC50 = 6 W). Diimidazoline 60 exhibited antiplasmodial IC50 value of 0.6 W. Seven congeners administered at 4 x 5 mg/kg by the intraperitoneal route cured at least three out
Perception of traffic noise emission in Basel City canton in comparison to actually measured noise levels (Publications)
asked how they perceived street traffic noise. The extent of annoyance was assessed with a scale from 0 (no annoyance) to 10 (unbearably annoyed). The actual noise levels were taken from the official noi
Incidence of asthma and net change in symptoms in relation to changes in obesity (Publications)
those never obese (hazard ratio 2.00, 95% confidence interval 1.25 to 3.20, excess net change 2.8%, 0.4 to 5.3%, per 10 years). The effect of being obese on net change in diagnosed asthma was greater in
<em>Ancylostoma caninum</em>: calibration and comparison of diagnostic accuracy of flotation in tube, McMaster and FLOTAC in faecal samples of dogs (Publications)
and flotation in tube. The best results in terms of mean faecal egg counts (highest value, i.e. 117.0 EPG) and CV (lowest value, i.e. 4.8%) were obtained with FLOTAC using sodium chloride and faecal samples
Human infections with <em>Dicrocoelium dendriticum</em> in Kyrgyzstan: the tip of the iceberg? (Publications)
subjected to the FLOTAC technique. Eggs of D. dendriticum were diagnosed in 11 children (prevalence 8.0%; 95% confidence interval 4.5-13.7%). Although no distinction could be made between true and pseudo
An unusual dimeric guaianolide with antiprotozoal activity and further sesquiterpene lactones from <em>Eupatorium perfoliatum</em> (Publications)
dimeric guaianolide was shown to be the most active constituent against Plasmodium falciparum (IC(50) = 2.0muM) and was less cytotoxic against rat skeletal myoblasts (IC(50) = 16.2muM, selectivity index of about
Maternal vitamin D intake during pregnancy increases gene expression of ILT3 and ILT4 in cord blood (Publications)
supplementation during pregnancy was associated with an increase in the gene expression of ILT3 (P=0.012) and ILT4 (P
Solid phase synthesis and antiprotozoal evaluation of di- and trisubstituted 5'-carboxamidoadenosine analogues (Publications)
compounds with promising activity: N(6)-benzyl-5'-N-phenylcarboxamidoadenosine with an IC(50) value of 0.91muM against Trypanosoma brucei rhodesiense and N(6)-diphenylethyl-5'-phenylcarboxamidoadenosine with
Socio-cultural determinants of anticipated acceptance of an oral cholera vaccine in western Kenya (Publications)
s. Nearly all (99%) residents indicated willingness to accept a no-cost OCV, 95% at a price of US$ 0.8, 73% at US$ 4.2 and 59% at US$ 8.4. Logistic regression models analysed socio-cultural determinants
Travellers' profile, travel patterns and vaccine practices - a 10-year prospective study in a Swiss Travel Clinic (Publications)
client-trips were recorded. Fifty-one percent clients were female. Mean age was 32 years. In total, 0.1% were aged /=80 years. Forty-six percent of travellers had pre-existing medical conditions. Forty-six