Epidemiology of schistosomiasis in two high-risk communities of south Côte d'Ivoire with particular emphasis on pre-school-aged children (Publications)
of Schistosoma mansoni in the two study villages among the pre-school-aged children was 20.9% and 25.0%, whereas several-fold higher prevalence was found in school-aged children (58.7-68.4%) and adolesc
Enantioselective synthesis of encecaline-derived potent antimalarial agents (Publications)
enantiomers. Phenol (R)- represents a very potent lead against P. falciparum, with an IC50 value of only 0.026 ?M against the NF54 strain. The very high eudismic ratio of 34 indicates the enantioselective i
Noise-related sleep disturbances: does gender matter? (Publications)
sleep duration in highly exposed men (> 55 dB) was reduced by 1.5 h (95% confidence interval [CI]: 2.3-0.8 h) compared with low exposed men (
Associations between air pollution and socioeconomic characteristics, ethnicity and age profile of neighbourhoods in England and the Netherlands (Publications)
NO2). Concentrations in both countries were higher in neighbourhoods with > 20% non-White (England: 3.0 µg/m(3) higher PM10 and 10.1 µg/m(3) NO2; the Netherlands: 1.1 µg/m(3) higher PM10 and 4.5 µg/m(3) NO2)
Antiprotozoal activity of (e)-cinnamic N-acylhydrazone derivatives (Publications)
antileishmanial activity (IC50 = 6.27 microM) when compared to miltefosine, the reference drug (IC50 = 0.348 microM). However, the elected compound showed an excellent selectivity index; in one case it was
Modelling the ecological niche of hookworm in Brazil based on climate (Publications)
Necator americanus) conditional on concurrent monthly values (rain/potential, evapotranspiration) of over 0.4. A second model, designated the gradient index, was calculated based on the monthly accumulation of
Cholesterol metabolites exported from human brain (Publications)
to be formed through reactive oxygen species, are similarly exported from brain at rates of about 0.1, 2 and 2mg/24h, respectively. Although not to statistical significance both GC-MS and liquid chro
Effects of filter choice in GT3X accelerometer assessments of free-living activity (Publications)
were established using linear regression models. RESULTS: Although Spearman correlations were high (r> 0.93), there were significant differences in minutes per day between filter options for non-wearing time
A common functional variant on the pro-inflammatory Interleukin-6 gene may modify the association between long-term PM10 exposure and diabetes (Publications)
physician-diagnosed, or use of diabetes medication or non-fasting glucose > 11.1 mmol/L or HbA1c > 0.065. Air pollution exposure was 10-year mean particulate matter
Genes and pathways underlying susceptibility to impaired lung function in the context of environmental tobacco smoke exposure (Publications)
exposure. METHODS: Genome-wide interactions of single nucleotide polymorphism (SNP) by ETS exposure (0 versus > /=1 h/day) in relation to the level of forced expiratory volume in one second (FEV1) were
