Transmission dynamics of highly pathogenic avian influenza at lake constance (Europe) during the outbreak of winter 2005-2006 (Publications)
compartment of the SIR model. The three transmission models predict a basic reproduction ratio (R (0)) with value of approximately 1.6, indicating a small epidemic, which ended with the migration of s
Chromosomal translocations t(4;14), t(11;14) and proliferation rate stratify patients with mature plasma cell myelomas into groups with different... (Publications)
morphology. Patients with a t(4;14) (12%) had a statistically significant shorter 1-year survival (P=0.004), whereas those with a t(11;14) (21%) had a trend towards a better clinical outcome. CyclinD1 protein
Line profile reconstruction: validation and comparison of reconstruction methods (Publications)
Of the four different release types, three were successfully reconstructed with CCFs greater than 0.9. The-difficult reconstruction involved a narrow release where the pollutant was limited to one segment
Spatial-temporal and cancer risk assessment of selected hazardous air pollutants in Seattle (Publications)
to HAPs. The median values of the estimated inhalation cancer risks ranged between 4.3x10(-5) and 6.0x10(-5), with the 5th and 95th percentile levels exceeding the 1 in a million level. VOCs as a whole
Antitrypanosomal isothiocyanate and thiocarbamate glycosides from <em>Moringa peregrina </em>[Letter] (Publications)
and cytotoxicity in rat skeletal myoblasts (L6 cells). The most potent compound was 4 with an IC50 of 0.10 microM against T. b. rhodesiense and a selectivity index of 73, while the thiocarbamate glycosides
Dose-response relationships and tegumental surface alterations in <em>Opisthorchis viverrini</em> following treatment with mefloquine in vivo and in... (Publications)
dose of 300-mg/kg mefloquine resulted in worm burden reductions of 88.5% (juvenile infection) and 96.0% (adult infections), respectively. Incubation with 10 and 100 microg/ml mefloquine resulted in rapid
Identification of new human malaria parasite <em>Plasmodium falciparum</em> dihydroorotate dehydrogenase inhibitors by pharmacophore and... (Publications)
inhibition of PfDHODH at a concentration of 10 muM, three of which exhibited IC50 values in the range of 0.38-20 muM. The most active compound, NSC336047, displayed species-selectivity for PfDHODH over human
Controlled human malaria infection of Tanzanians by intradermal injection of aseptic, purified, cryopreserved <em>Plasmodium falciparum</em>... (Publications)
groups geometric mean days from injection to Pf positivity by thick blood film was 15.4 versus 13.5 (P = 0.023). Alpha-thalassemia heterozygosity had no apparent effect on infectivity. PfSPZ Challenge was safe
Carotid stiffness and physical activity in elderly: a short report of the SAPALDIA 3 cohort study (Publications)
and 95% confidence interval per 1 standard deviation increment in vigorous physical activity = 2.54 (0.69; 4.43), p
Bifurcatriol, a new antiprotozoal acyclic diterpene from the brown alga <em>Bifurcaria bifurcata</em> (Publications)
primary cells. The highest activity was exerted against the malaria parasite P. falciparum (IC50 value 0.65 mug/mL) with low cytotoxicity (IC50 value 56.6 mug/mL). To our knowledge, this is the first successful
